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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
29.09
Human Site:
S112
Identified Species:
49.23
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
S112
L
L
V
I
G
G
S
S
E
R
N
Q
E
T
M
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
S112
L
L
V
I
G
G
S
S
E
R
N
Q
E
T
M
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
Y54
A
Q
Q
L
G
I
K
Y
I
G
M
R
N
E
Q
Dog
Lupus familis
XP_534256
667
72859
S201
L
I
V
I
G
G
S
S
E
R
R
Q
E
T
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
S115
L
I
V
I
G
G
S
S
E
R
N
Q
E
A
M
Rat
Rattus norvegicus
Q8CHM7
581
63598
S115
L
I
V
I
G
G
S
S
E
R
N
Q
E
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
S102
L
I
V
I
G
G
S
S
D
R
N
Q
E
T
M
Frog
Xenopus laevis
Q6DDK5
649
71410
A136
I
V
L
L
A
G
A
A
A
G
L
L
R
G
R
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
A139
L
L
L
I
G
G
A
A
A
T
L
L
Q
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
T102
L
I
V
I
G
G
A
T
N
Q
D
H
E
G
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
A154
L
L
L
I
G
G
A
A
P
T
L
L
K
G
R
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
V94
P
F
F
V
E
K
A
V
R
I
S
T
H
G
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
V196
L
V
A
I
T
G
Q
V
P
R
R
M
I
G
T
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
S101
L
L
V
I
A
G
S
S
S
Q
S
D
I
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
86.6
6.6
33.3
N.A.
40
N.A.
33.3
0
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
46.6
60
N.A.
80
N.A.
60
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
15
0
36
22
15
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% D
% Glu:
0
0
0
0
8
0
0
0
36
0
0
0
50
8
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
72
86
0
0
0
15
0
0
0
43
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
8
8
0
% H
% Ile:
8
36
0
79
0
8
0
0
8
8
0
0
15
0
8
% I
% Lys:
0
0
0
0
0
8
8
0
0
0
0
0
8
0
8
% K
% Leu:
79
36
22
15
0
0
0
0
0
0
22
22
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
43
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
36
0
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
0
8
0
0
15
0
43
8
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
50
15
8
8
0
29
% R
% Ser:
0
0
0
0
0
0
50
50
8
0
15
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
8
0
15
0
8
0
29
8
% T
% Val:
0
15
58
8
0
0
0
15
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _