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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
7.88
Human Site:
S192
Identified Species:
13.33
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
S192
K
Y
M
E
R
C
M
S
P
P
I
S
M
A
E
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
S192
K
Y
M
E
R
C
M
S
P
P
I
S
M
A
E
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
R132
F
F
S
R
H
V
E
R
C
M
S
P
P
I
S
Dog
Lupus familis
XP_534256
667
72859
P281
K
Y
V
E
C
C
L
P
P
P
V
S
M
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
P195
K
Y
K
E
C
C
M
P
P
P
V
S
M
A
E
Rat
Rattus norvegicus
Q8CHM7
581
63598
P195
K
Y
K
E
C
C
M
P
P
P
L
S
L
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
P182
K
Y
V
E
C
C
P
P
P
P
I
S
T
A
E
Frog
Xenopus laevis
Q6DDK5
649
71410
N224
S
W
R
Q
R
F
T
N
W
Y
L
R
F
Y
L
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
S248
A
W
E
S
R
D
L
S
P
L
P
V
H
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
A182
Y
K
A
L
A
H
P
A
P
P
L
A
Y
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
P266
P
Q
T
I
T
P
L
P
T
N
I
P
M
P
K
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
V172
Y
A
R
A
E
K
E
V
R
A
F
L
D
Q
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
G275
E
Q
A
M
R
L
P
G
Y
M
S
R
M
P
K
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
T184
N
E
L
P
M
I
L
T
P
N
I
C
G
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
0
66.6
N.A.
73.3
66.6
N.A.
N.A.
66.6
6.6
20
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
100
6.6
86.6
N.A.
80
80
N.A.
N.A.
73.3
33.3
33.3
N.A.
33.3
N.A.
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
8
8
0
0
8
0
8
0
8
0
43
0
% A
% Cys:
0
0
0
0
29
43
0
0
8
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
8
% D
% Glu:
8
8
8
43
8
0
15
0
0
0
0
0
0
0
43
% E
% Phe:
8
8
0
0
0
8
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
8
0
0
0
0
36
0
0
15
0
% I
% Lys:
43
8
15
0
0
8
0
0
0
0
0
0
0
0
15
% K
% Leu:
0
0
8
8
0
8
29
0
0
8
22
8
8
0
8
% L
% Met:
0
0
15
8
8
0
29
0
0
15
0
0
43
0
0
% M
% Asn:
8
0
0
0
0
0
0
8
0
15
0
0
0
0
0
% N
% Pro:
8
0
0
8
0
8
22
36
65
50
8
15
8
29
15
% P
% Gln:
0
15
0
8
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
15
8
36
0
0
8
8
0
0
15
0
0
0
% R
% Ser:
8
0
8
8
0
0
0
22
0
0
15
43
0
0
8
% S
% Thr:
0
0
8
0
8
0
8
8
8
0
0
0
8
0
8
% T
% Val:
0
0
15
0
0
8
0
8
0
0
15
8
0
0
0
% V
% Trp:
0
15
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
15
43
0
0
0
0
0
0
8
8
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _