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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
15.45
Human Site:
S545
Identified Species:
26.15
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
S545
L
Q
K
S
L
R
Q
S
L
A
D
T
T
K
P
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
S545
L
Q
K
S
L
R
Q
S
L
A
D
T
T
K
P
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
L455
Q
K
S
L
R
Q
S
L
A
D
T
A
K
P
S
Dog
Lupus familis
XP_534256
667
72859
S634
L
Q
K
S
L
R
E
S
L
A
D
T
T
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
A548
L
Q
H
S
L
R
Q
A
L
Q
D
T
S
K
P
Rat
Rattus norvegicus
Q8CHM7
581
63598
A548
L
Q
D
S
L
R
Q
A
L
K
D
T
S
K
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
S535
L
Q
N
A
V
K
A
S
L
A
D
K
Q
T
P
Frog
Xenopus laevis
Q6DDK5
649
71410
S615
E
K
N
L
D
N
L
S
D
Y
M
A
H
A
R
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
I589
D
E
S
Q
L
E
D
I
I
K
K
A
Q
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
A535
L
Q
A
A
V
K
A
A
N
Q
L
T
D
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
S599
W
G
E
T
I
D
E
S
N
A
D
S
A
R
K
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
K495
A
L
R
L
S
L
T
K
H
A
N
Q
P
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
M628
L
R
E
A
I
Q
T
M
L
D
T
P
G
P
Y
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
A525
L
S
R
C
F
Q
Q
A
V
Q
L
S
R
T
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
0
93.3
N.A.
73.3
73.3
N.A.
N.A.
46.6
6.6
13.3
N.A.
26.6
N.A.
20
6.6
P-Site Similarity:
100
100
13.3
100
N.A.
86.6
86.6
N.A.
N.A.
66.6
13.3
26.6
N.A.
60
N.A.
60
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
22
0
0
15
29
8
43
0
22
8
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
8
8
0
8
15
50
0
8
0
0
% D
% Glu:
8
8
15
0
0
8
15
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
15
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
0
15
22
0
0
15
0
8
0
15
8
8
8
43
15
% K
% Leu:
65
8
0
22
43
8
8
8
50
0
15
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% M
% Asn:
0
0
15
0
0
8
0
0
15
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
8
15
50
% P
% Gln:
8
50
0
8
0
22
36
0
0
22
0
8
15
0
0
% Q
% Arg:
0
8
15
0
8
36
0
0
0
0
0
0
8
15
8
% R
% Ser:
0
8
15
36
8
0
8
43
0
0
0
15
15
0
8
% S
% Thr:
0
0
0
8
0
0
15
0
0
0
15
43
22
15
0
% T
% Val:
0
0
0
0
15
0
0
0
8
0
0
0
0
8
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _