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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
15.45
Human Site:
S553
Identified Species:
26.15
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
S553
L
A
D
T
T
K
P
S
L
I
N
I
M
I
E
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
S553
L
A
D
T
T
K
P
S
L
I
N
V
M
I
E
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
L463
A
D
T
A
K
P
S
L
I
N
I
M
I
E
P
Dog
Lupus familis
XP_534256
667
72859
S642
L
A
D
T
T
K
P
S
L
I
N
I
M
I
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
C556
L
Q
D
T
S
K
P
C
L
L
N
I
M
I
E
Rat
Rattus norvegicus
Q8CHM7
581
63598
C556
L
K
D
T
S
K
P
C
L
I
N
I
M
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
S543
L
A
D
K
Q
T
P
S
L
I
N
V
M
I
D
Frog
Xenopus laevis
Q6DDK5
649
71410
E623
D
Y
M
A
H
A
R
E
L
S
D
R
G
L
P
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
C597
I
K
K
A
Q
K
E
C
K
E
G
K
A
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
T543
N
Q
L
T
D
R
P
T
I
I
N
V
A
I
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
I607
N
A
D
S
A
R
K
I
L
D
E
A
L
A
V
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
I503
H
A
N
Q
P
V
L
I
N
V
M
V
S
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
L636
L
D
T
P
G
P
Y
L
L
D
V
I
C
P
H
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
R533
V
Q
L
S
R
T
K
R
E
T
S
V
I
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
93.3
0
100
N.A.
73.3
80
N.A.
N.A.
66.6
6.6
6.6
N.A.
33.3
N.A.
20
6.6
P-Site Similarity:
100
100
20
100
N.A.
86.6
86.6
N.A.
N.A.
80
20
20
N.A.
60
N.A.
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
43
0
22
8
8
0
0
0
0
0
8
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
22
0
0
0
0
8
0
0
% C
% Asp:
8
15
50
0
8
0
0
0
0
15
8
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
8
8
8
8
8
0
0
8
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
8
0
8
0
0
% G
% His:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
15
15
43
8
36
15
50
0
% I
% Lys:
0
15
8
8
8
43
15
0
8
0
0
8
0
0
0
% K
% Leu:
50
0
15
0
0
0
8
15
65
8
0
0
8
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
8
43
0
0
% M
% Asn:
15
0
8
0
0
0
0
0
8
8
50
0
0
8
0
% N
% Pro:
0
0
0
8
8
15
50
0
0
0
0
0
0
15
15
% P
% Gln:
0
22
0
8
15
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
8
15
8
8
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
15
15
0
8
29
0
8
8
0
8
0
8
% S
% Thr:
0
0
15
43
22
15
0
8
0
8
0
0
0
0
0
% T
% Val:
8
0
0
0
0
8
0
0
0
8
8
36
0
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _