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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
15.45
Human Site:
T339
Identified Species:
26.15
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
T339
L
L
E
E
L
D
K
T
P
W
Q
Y
P
P
E
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
T339
L
L
E
E
L
D
K
T
P
W
Q
Y
P
P
E
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
E253
Q
V
D
I
C
A
E
E
L
G
N
N
V
K
P
Dog
Lupus familis
XP_534256
667
72859
T428
L
L
E
Q
F
D
K
T
P
W
Q
Y
P
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
T342
L
L
E
Q
F
D
K
T
P
W
Q
C
P
P
D
Rat
Rattus norvegicus
Q8CHM7
581
63598
N342
L
L
E
Q
F
V
K
N
P
W
Q
Y
P
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
R329
L
L
E
E
F
S
K
R
P
L
K
Y
P
S
N
Frog
Xenopus laevis
Q6DDK5
649
71410
D413
D
R
F
P
C
L
S
D
F
R
C
P
T
E
W
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
T380
S
D
M
F
W
K
P
T
V
A
I
Q
G
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
V329
L
F
E
Q
M
N
A
V
N
F
R
F
G
Y
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
W392
T
K
N
E
K
A
F
W
N
S
D
V
S
V
Q
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
T293
G
W
S
Y
P
S
N
T
P
W
W
Q
S
L
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
V425
A
L
Q
G
M
N
K
V
L
E
N
R
A
E
E
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
S323
I
W
G
D
I
G
L
S
V
T
A
L
V
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
0
86.6
N.A.
73.3
60
N.A.
N.A.
53.3
0
6.6
N.A.
20
N.A.
6.6
20
P-Site Similarity:
100
100
20
93.3
N.A.
86.6
73.3
N.A.
N.A.
60
0
6.6
N.A.
60
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
15
8
0
0
8
8
0
8
0
8
% A
% Cys:
0
0
0
0
15
0
0
0
0
0
8
8
0
0
0
% C
% Asp:
8
8
8
8
0
29
0
8
0
0
8
0
0
8
15
% D
% Glu:
0
0
50
29
0
0
8
8
0
8
0
0
0
22
43
% E
% Phe:
0
8
8
8
29
0
8
0
8
8
0
8
0
0
0
% F
% Gly:
8
0
8
8
0
8
0
0
0
8
0
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
8
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
0
0
8
8
50
0
0
0
8
0
0
8
0
% K
% Leu:
50
50
0
0
15
8
8
0
15
8
0
8
0
8
0
% L
% Met:
0
0
8
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
15
8
8
15
0
15
8
0
0
8
% N
% Pro:
0
0
0
8
8
0
8
0
50
0
0
8
43
29
8
% P
% Gln:
8
0
8
29
0
0
0
0
0
0
36
15
0
0
8
% Q
% Arg:
0
8
0
0
0
0
0
8
0
8
8
8
0
0
8
% R
% Ser:
8
0
8
0
0
15
8
8
0
8
0
0
15
8
0
% S
% Thr:
8
0
0
0
0
0
0
43
0
8
0
0
8
8
0
% T
% Val:
0
8
0
0
0
8
0
15
15
0
0
8
15
8
0
% V
% Trp:
0
15
0
0
8
0
0
8
0
43
8
0
0
0
8
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
36
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _