KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
20
Human Site:
T352
Identified Species:
33.85
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
T352
P
E
S
K
W
W
K
T
L
R
E
K
M
K
S
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
T352
P
E
S
K
W
W
K
T
L
R
E
K
M
K
S
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
G266
K
P
A
V
T
L
L
G
D
I
N
A
V
T
K
Dog
Lupus familis
XP_534256
667
72859
T441
P
E
S
S
W
W
Q
T
L
R
E
K
M
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
T355
P
D
S
Q
W
W
K
T
L
R
E
K
M
K
S
Rat
Rattus norvegicus
Q8CHM7
581
63598
T355
T
D
S
K
W
W
E
T
L
R
E
K
R
K
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
K342
S
N
S
E
W
W
K
K
L
R
E
K
M
L
N
Frog
Xenopus laevis
Q6DDK5
649
71410
A426
E
W
V
G
E
L
L
A
R
E
H
H
R
D
E
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
N393
D
A
G
S
F
L
L
N
L
S
K
A
L
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
Q342
Y
E
Q
D
W
W
K
Q
L
A
V
K
C
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
S405
V
Q
A
D
V
A
T
S
L
V
Q
V
A
N
A
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
N306
L
R
S
K
V
K
D
N
E
E
K
S
K
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
G438
E
E
L
K
L
D
F
G
V
W
R
N
E
L
N
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
S336
E
E
L
T
R
Q
D
S
C
W
K
Y
S
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
0
80
N.A.
86.6
66.6
N.A.
N.A.
60
0
13.3
N.A.
46.6
N.A.
6.6
13.3
P-Site Similarity:
100
100
13.3
93.3
N.A.
100
86.6
N.A.
N.A.
73.3
0
33.3
N.A.
46.6
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
15
0
0
8
0
8
0
8
0
15
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% C
% Asp:
8
15
0
15
0
8
15
0
8
0
0
0
0
8
0
% D
% Glu:
22
43
0
8
8
0
8
0
8
15
43
0
8
8
8
% E
% Phe:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
15
0
0
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
8
0
0
36
0
8
36
8
0
0
22
50
8
43
8
% K
% Leu:
8
0
15
0
8
22
22
0
65
0
0
0
8
15
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
36
0
0
% M
% Asn:
0
8
0
0
0
0
0
15
0
0
8
8
0
8
22
% N
% Pro:
29
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
8
8
0
8
8
8
0
0
8
0
0
0
8
% Q
% Arg:
0
8
0
0
8
0
0
0
8
43
8
0
15
0
0
% R
% Ser:
8
0
50
15
0
0
0
15
0
8
0
8
8
0
29
% S
% Thr:
8
0
0
8
8
0
8
36
0
0
0
0
0
8
0
% T
% Val:
8
0
8
8
15
0
0
0
8
8
8
8
8
0
8
% V
% Trp:
0
8
0
0
50
50
0
0
0
15
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _