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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
28.79
Human Site:
T422
Identified Species:
48.72
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
T422
R
H
R
L
D
A
G
T
F
G
T
M
G
V
G
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
T422
R
H
R
L
D
A
G
T
F
G
T
M
G
V
G
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
G336
A
G
T
F
G
T
M
G
V
G
L
G
F
A
I
Dog
Lupus familis
XP_534256
667
72859
T511
R
H
R
L
D
A
G
T
F
G
T
M
G
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
S425
R
H
R
L
D
A
G
S
F
G
T
M
G
V
G
Rat
Rattus norvegicus
Q8CHM7
581
63598
S425
R
H
R
L
D
A
G
S
F
G
T
M
G
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
T412
R
Q
R
L
D
A
G
T
F
G
T
M
G
V
G
Frog
Xenopus laevis
Q6DDK5
649
71410
P496
L
S
W
L
D
P
G
P
F
G
T
L
G
V
G
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
S463
D
G
G
D
F
V
G
S
A
A
Y
I
M
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
T412
R
H
R
L
D
A
G
T
F
G
T
M
G
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
G475
D
A
I
L
V
A
D
G
G
D
F
V
G
S
A
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
M376
F
G
T
M
G
V
G
M
G
F
N
I
A
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
G508
P
R
Q
W
L
S
S
G
G
L
G
A
M
G
F
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
T406
I
A
R
I
S
F
P
T
D
A
P
R
R
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
6.6
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
60
6.6
N.A.
100
N.A.
20
6.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
93.3
66.6
20
N.A.
100
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
0
0
58
0
0
8
15
0
8
8
15
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
8
58
0
8
0
8
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
8
8
8
0
0
58
8
8
0
8
0
8
% F
% Gly:
0
22
8
0
15
0
72
22
22
65
8
8
65
8
58
% G
% His:
0
43
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
8
0
0
0
0
0
0
0
15
0
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
65
8
0
0
0
0
8
8
8
0
0
8
% L
% Met:
0
0
0
8
0
0
8
8
0
0
0
50
15
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
0
0
0
0
8
8
8
0
0
8
0
0
0
8
% P
% Gln:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
50
8
58
0
0
0
0
0
0
0
0
8
8
15
0
% R
% Ser:
0
8
0
0
8
8
8
22
0
0
0
0
0
8
0
% S
% Thr:
0
0
15
0
0
8
0
43
0
0
58
0
0
0
0
% T
% Val:
0
0
0
0
8
15
0
0
8
0
0
8
0
58
0
% V
% Trp:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _