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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
22.73
Human Site:
T523
Identified Species:
38.46
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
T523
S
H
Y
E
Q
V
M
T
A
F
G
G
K
G
Y
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
T523
S
H
Y
E
Q
V
M
T
A
F
G
G
K
G
Y
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
A433
H
Y
E
Q
V
M
T
A
F
G
G
K
G
Y
F
Dog
Lupus familis
XP_534256
667
72859
T612
S
H
Y
E
Q
V
M
T
A
F
G
G
K
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
T526
S
H
Y
E
Q
V
M
T
A
F
G
G
K
G
Y
Rat
Rattus norvegicus
Q8CHM7
581
63598
T526
S
H
Y
E
Q
V
M
T
A
F
G
G
K
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
S513
A
H
Y
E
E
I
M
S
A
F
G
G
K
G
Y
Frog
Xenopus laevis
Q6DDK5
649
71410
N593
Y
A
G
A
D
P
L
N
S
T
L
S
V
E
D
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
V567
A
F
T
D
Y
H
V
V
A
D
G
Y
G
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
K513
V
R
Y
E
E
M
M
K
M
F
G
M
K
G
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
L577
Q
S
S
V
A
V
D
L
A
R
T
R
Y
D
N
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
G473
D
Q
V
M
T
A
F
G
G
V
G
F
H
V
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
A606
P
N
M
L
L
F
A
A
A
C
G
I
P
A
A
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
K503
C
R
Y
D
L
V
G
K
G
L
G
A
N
D
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
73.3
0
20
N.A.
53.3
N.A.
13.3
6.6
P-Site Similarity:
100
100
33.3
100
N.A.
100
100
N.A.
N.A.
100
13.3
40
N.A.
66.6
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
0
8
8
8
8
15
65
0
0
8
0
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
15
8
0
8
0
0
8
0
0
0
15
8
% D
% Glu:
0
0
8
50
15
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
8
0
0
0
8
8
0
8
50
0
8
0
0
15
% F
% Gly:
0
0
8
0
0
0
8
8
15
8
86
43
15
58
0
% G
% His:
8
43
0
0
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
15
0
0
0
8
50
0
8
% K
% Leu:
0
0
0
8
15
0
8
8
0
8
8
0
0
0
0
% L
% Met:
0
0
8
8
0
15
50
0
8
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
0
0
8
0
8
% N
% Pro:
8
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
8
0
8
36
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
15
0
0
0
0
0
0
0
8
0
8
0
0
0
% R
% Ser:
36
8
8
0
0
0
0
8
8
0
0
8
0
0
0
% S
% Thr:
0
0
8
0
8
0
8
36
0
8
8
0
0
0
8
% T
% Val:
8
0
8
8
8
50
8
8
0
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
58
0
8
0
0
0
0
0
0
8
8
8
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _