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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
4.55
Human Site:
Y260
Identified Species:
7.69
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
Y260
V
V
P
D
N
H
P
Y
C
V
G
A
A
R
S
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
Y260
V
V
P
D
N
H
P
Y
C
V
G
A
A
R
S
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
V197
T
P
M
G
K
G
V
V
P
D
N
H
P
Y
C
Dog
Lupus familis
XP_534256
667
72859
N349
V
V
P
D
N
H
P
N
C
V
S
A
A
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
N263
V
V
P
D
N
H
P
N
C
V
G
A
A
R
S
Rat
Rattus norvegicus
Q8CHM7
581
63598
N263
V
V
P
D
N
H
P
N
C
V
G
A
A
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
N250
V
V
P
D
N
H
P
N
C
V
A
A
A
R
S
Frog
Xenopus laevis
Q6DDK5
649
71410
C326
L
L
G
R
H
H
P
C
V
F
R
H
A
R
R
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
L320
L
L
G
K
N
S
P
L
H
I
R
Q
N
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
Q250
V
V
S
D
T
A
P
Q
C
V
S
S
A
R
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
L335
L
L
G
K
D
H
P
L
Q
M
R
Q
V
R
R
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
E237
R
P
P
R
F
G
E
E
T
K
F
I
Q
I
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
L344
S
Y
P
C
D
D
E
L
S
L
H
M
L
G
M
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
L252
I
V
P
D
S
S
P
L
N
V
S
S
A
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
0
86.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
26.6
20
N.A.
53.3
N.A.
20
6.6
P-Site Similarity:
100
100
0
86.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
46.6
40
N.A.
66.6
N.A.
46.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
8
43
65
0
0
% A
% Cys:
0
0
0
8
0
0
0
8
50
0
0
0
0
0
8
% C
% Asp:
0
0
0
58
15
8
0
0
0
8
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
15
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
22
8
0
15
0
0
0
0
29
0
0
8
0
% G
% His:
0
0
0
0
8
58
0
0
8
0
8
15
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% I
% Lys:
0
0
0
15
8
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
22
22
0
0
0
0
0
29
0
8
0
0
8
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
8
0
8
0
0
8
% M
% Asn:
0
0
0
0
50
0
0
29
8
0
8
0
8
0
0
% N
% Pro:
0
15
65
0
0
0
79
0
8
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
8
0
0
15
8
0
0
% Q
% Arg:
8
0
0
15
0
0
0
0
0
0
22
0
0
79
22
% R
% Ser:
8
0
8
0
8
15
0
0
8
0
22
15
0
0
50
% S
% Thr:
8
0
0
0
8
0
0
0
8
0
0
0
0
0
8
% T
% Val:
50
58
0
0
0
0
8
8
8
58
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
15
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _