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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
25.76
Human Site:
Y378
Identified Species:
43.59
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
Y378
K
S
L
P
M
N
Y
Y
T
V
F
Y
H
V
Q
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
Y378
K
S
L
P
M
N
Y
Y
T
V
F
Y
H
I
Q
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
H292
N
Y
Y
T
V
F
Y
H
V
Q
E
Q
L
P
R
Dog
Lupus familis
XP_534256
667
72859
Y467
K
S
L
P
M
N
Y
Y
T
V
F
Y
Q
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
Y381
K
S
L
P
M
N
Y
Y
T
V
F
Y
H
V
Q
Rat
Rattus norvegicus
Q8CHM7
581
63598
Y381
K
S
L
P
M
N
Y
Y
T
V
F
Y
H
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
Y368
K
S
L
P
M
N
Y
Y
T
V
F
H
H
I
R
Frog
Xenopus laevis
Q6DDK5
649
71410
V452
E
R
I
N
P
L
S
V
L
W
Q
L
E
H
N
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
E419
K
E
G
D
N
V
K
E
K
A
N
R
A
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
Y368
T
E
T
P
L
N
Y
Y
A
V
F
H
H
L
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
K431
W
V
K
S
L
R
E
K
D
D
E
K
E
S
A
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
A332
A
A
I
S
K
V
Q
A
M
I
P
K
D
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
P464
T
F
G
E
A
I
P
P
Q
Y
A
I
K
V
L
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
E362
Q
T
R
L
L
R
K
E
K
T
R
G
A
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
93.3
6.6
93.3
N.A.
100
100
N.A.
N.A.
80
0
6.6
N.A.
46.6
N.A.
0
0
P-Site Similarity:
100
100
26.6
93.3
N.A.
100
100
N.A.
N.A.
100
13.3
6.6
N.A.
73.3
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
0
8
8
8
8
0
15
0
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
8
0
0
8
0
0
% D
% Glu:
8
15
0
8
0
0
8
15
0
0
15
0
15
0
0
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
50
0
0
0
0
% F
% Gly:
0
0
15
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
15
43
8
0
% H
% Ile:
0
0
15
0
0
8
0
0
0
8
0
8
0
15
0
% I
% Lys:
50
0
8
0
8
0
15
8
15
0
0
15
8
8
0
% K
% Leu:
0
0
43
8
22
8
0
0
8
0
0
8
8
8
22
% L
% Met:
0
0
0
0
43
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
8
50
0
0
0
0
8
0
0
0
8
% N
% Pro:
0
0
0
50
8
0
8
8
0
0
8
0
0
8
0
% P
% Gln:
8
0
0
0
0
0
8
0
8
8
8
8
8
8
36
% Q
% Arg:
0
8
8
0
0
15
0
0
0
0
8
8
0
0
22
% R
% Ser:
0
43
0
15
0
0
8
0
0
0
0
0
0
15
0
% S
% Thr:
15
8
8
8
0
0
0
0
43
8
0
0
0
0
0
% T
% Val:
0
8
0
0
8
15
0
8
8
50
0
0
0
36
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
8
8
0
0
0
58
50
0
8
0
36
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _