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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
18.79
Human Site:
Y54
Identified Species:
31.79
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
Y54
A
Q
Q
L
G
I
K
Y
I
G
M
R
N
E
Q
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
Y54
A
Q
Q
L
G
I
K
Y
I
G
M
R
N
E
Q
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
E8
M
P
D
S
N
F
A
E
R
S
E
E
Q
V
S
Dog
Lupus familis
XP_534256
667
72859
Y143
A
Q
K
L
G
I
R
Y
V
G
M
R
N
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
Y57
A
Q
E
L
G
I
K
Y
I
G
M
R
N
E
Q
Rat
Rattus norvegicus
Q8CHM7
581
63598
Y57
A
Q
E
L
G
I
K
Y
I
G
M
R
N
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
C54
M
R
N
E
Q
A
A
C
Y
A
A
S
A
V
G
Frog
Xenopus laevis
Q6DDK5
649
71410
V78
A
E
R
Q
N
I
R
V
I
D
V
R
H
E
A
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
I81
C
E
K
L
G
I
R
I
V
D
T
R
H
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
A56
N
E
Q
A
A
C
Y
A
A
Q
A
I
G
Y
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
I96
A
E
K
L
G
I
K
I
V
D
T
R
H
E
V
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
G48
A
W
P
V
I
V
I
G
G
S
S
D
E
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
N138
T
R
S
S
S
I
R
N
V
L
P
R
H
E
Q
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
Y54
R
N
E
Q
A
A
S
Y
A
A
S
A
Y
G
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
0
80
N.A.
93.3
93.3
N.A.
N.A.
0
33.3
33.3
N.A.
6.6
N.A.
46.6
13.3
P-Site Similarity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
6.6
66.6
66.6
N.A.
13.3
N.A.
73.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
58
0
0
8
15
15
15
8
15
15
15
8
8
0
15
% A
% Cys:
8
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
0
22
0
8
0
8
0
% D
% Glu:
0
29
22
8
0
0
0
8
0
0
8
8
8
65
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
50
0
0
8
8
36
0
0
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% H
% Ile:
0
0
0
0
8
65
8
15
36
0
0
8
0
0
0
% I
% Lys:
0
0
22
0
0
0
36
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
50
0
0
0
0
0
8
0
0
0
0
8
% L
% Met:
15
0
0
0
0
0
0
0
0
0
36
0
0
0
0
% M
% Asn:
8
8
8
0
15
0
0
8
0
0
0
0
36
0
0
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
36
22
15
8
0
0
0
0
8
0
0
8
0
50
% Q
% Arg:
8
15
8
0
0
0
29
0
8
0
0
65
0
0
0
% R
% Ser:
0
0
8
15
8
0
8
0
0
15
15
8
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
15
0
0
0
0
% T
% Val:
0
0
0
8
0
8
0
8
29
0
8
0
0
15
8
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
43
8
0
0
0
8
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _