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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HACL1
All Species:
18.18
Human Site:
Y65
Identified Species:
30.77
UniProt:
Q9UJ83
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJ83
NP_036392.2
578
63729
Y65
R
N
E
Q
A
A
C
Y
A
A
S
A
I
G
Y
Chimpanzee
Pan troglodytes
XP_001160528
578
63740
Y65
R
N
E
Q
A
A
C
Y
A
A
S
A
I
G
Y
Rhesus Macaque
Macaca mulatta
XP_001082965
487
53660
V19
E
Q
V
S
G
A
K
V
I
A
Q
A
L
K
T
Dog
Lupus familis
XP_534256
667
72859
Y154
R
N
E
Q
A
A
C
Y
A
A
S
A
V
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXE0
581
63642
Y68
R
N
E
Q
A
A
C
Y
A
A
S
A
V
G
Y
Rat
Rattus norvegicus
Q8CHM7
581
63598
Y68
R
N
E
Q
A
A
C
Y
A
A
S
A
V
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418737
568
61990
G65
S
A
V
G
Y
L
T
G
R
P
G
V
C
L
V
Frog
Xenopus laevis
Q6DDK5
649
71410
F89
R
H
E
A
S
A
V
F
A
A
D
A
V
S
R
Zebra Danio
Brachydanio rerio
Q6NV04
621
67017
F92
R
H
E
A
T
A
V
F
A
A
D
A
V
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611460
568
62246
P67
I
G
Y
L
T
G
K
P
G
V
C
L
V
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O61856
640
69245
F107
R
H
E
V
T
A
V
F
A
A
D
A
V
A
R
Sea Urchin
Strong. purpuratus
XP_001202799
527
57629
G59
D
E
D
Q
E
G
T
G
A
F
Q
E
W
P
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P17597
670
72567
F149
R
H
E
Q
G
G
V
F
A
A
E
G
Y
A
R
Baker's Yeast
Sacchar. cerevisiae
P39994
560
61270
K65
A
Y
G
Y
I
S
D
K
P
G
V
L
L
I
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
79.9
77.3
N.A.
87.4
85.5
N.A.
N.A.
72.6
22.5
24.1
N.A.
53.1
N.A.
26.4
52.6
Protein Similarity:
100
99.8
82.3
83
N.A.
93.9
92.9
N.A.
N.A.
85.2
43.9
43.1
N.A.
70.5
N.A.
46.2
67.3
P-Site Identity:
100
100
20
93.3
N.A.
93.3
93.3
N.A.
N.A.
0
40
40
N.A.
0
N.A.
40
13.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
N.A.
0
66.6
60
N.A.
6.6
N.A.
60
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.3
39.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.5
58.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
15
36
65
0
0
72
72
0
65
0
22
0
% A
% Cys:
0
0
0
0
0
0
36
0
0
0
8
0
8
0
0
% C
% Asp:
8
0
8
0
0
0
8
0
0
0
22
0
0
0
0
% D
% Glu:
8
8
65
0
8
0
0
0
0
0
8
8
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
29
0
8
0
0
0
0
0
% F
% Gly:
0
8
8
8
15
22
0
15
8
8
8
8
0
36
0
% G
% His:
0
29
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
0
0
0
8
0
0
0
15
8
0
% I
% Lys:
0
0
0
0
0
0
15
8
0
0
0
0
0
8
0
% K
% Leu:
0
0
0
8
0
8
0
0
0
0
0
15
15
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
36
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
8
0
0
0
8
0
% P
% Gln:
0
8
0
50
0
0
0
0
0
0
15
0
0
0
8
% Q
% Arg:
65
0
0
0
0
0
0
0
8
0
0
0
0
0
29
% R
% Ser:
8
0
0
8
8
8
0
0
0
0
36
0
0
8
8
% S
% Thr:
0
0
0
0
22
0
15
0
0
0
0
0
0
0
8
% T
% Val:
0
0
15
8
0
0
29
8
0
8
8
8
50
8
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
8
8
8
8
0
0
36
0
0
0
0
8
0
36
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _