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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDH22 All Species: 3.94
Human Site: S686 Identified Species: 9.63
UniProt: Q9UJ99 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJ99 NP_067071.1 828 89091 S686 D T E A Y D M S A L R S L Y D
Chimpanzee Pan troglodytes XP_525344 659 70856 Y518 G E Q D T E A Y D M S A L R S
Rhesus Macaque Macaca mulatta XP_001104171 835 89101 Y693 M S A L R S L Y D F G E L K G
Dog Lupus familis XP_543030 825 88615 Y683 G E Q D T E A Y D M S A L R S
Cat Felis silvestris
Mouse Mus musculus Q9WTP5 813 88003 G671 V I K Y N D E G G G E Q D T E
Rat Rattus norvegicus Q63315 813 87960 G671 V I K Y N D E G G G E Q D T E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507828 874 96521 V733 E E D V R E N V V T Y D D E G
Chicken Gallus gallus Q90763 785 87153 R644 P L I F D E E R D I R E N I V
Frog Xenopus laevis Q91838 790 88487 D649 P Y T I D E E D N V H E N I V
Zebra Danio Brachydanio rerio NP_001070916 787 86379 D646 E D R D V R E D I V R Y D D E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.8 88.5 96.6 N.A. 93 92.8 N.A. 49.6 53 49 50.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 77.7 92 97.8 N.A. 94.6 94.4 N.A. 66.3 70 66.6 67.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 6.6 N.A. 6.6 6.6 N.A. 0 6.6 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 33.3 20 33.3 N.A. 20 20 N.A. 20 20 13.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 0 20 0 10 0 0 20 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 10 30 20 30 0 20 40 0 0 10 40 10 10 % D
% Glu: 20 30 10 0 0 50 50 0 0 0 20 30 0 10 30 % E
% Phe: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 20 0 0 0 0 0 0 20 20 20 10 0 0 0 20 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 20 10 10 0 0 0 0 10 10 0 0 0 20 0 % I
% Lys: 0 0 20 0 0 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 10 0 10 0 0 10 0 0 10 0 0 40 0 0 % L
% Met: 10 0 0 0 0 0 10 0 0 20 0 0 0 0 0 % M
% Asn: 0 0 0 0 20 0 10 0 10 0 0 0 20 0 0 % N
% Pro: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 20 0 0 0 0 0 0 0 0 20 0 0 0 % Q
% Arg: 0 0 10 0 20 10 0 10 0 0 30 0 0 20 0 % R
% Ser: 0 10 0 0 0 10 0 10 0 0 20 10 0 0 20 % S
% Thr: 0 10 10 0 20 0 0 0 0 10 0 0 0 20 0 % T
% Val: 20 0 0 10 10 0 0 10 10 20 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 20 10 0 0 30 0 0 10 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _