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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDH22 All Species: 1.82
Human Site: T680 Identified Species: 4.44
UniProt: Q9UJ99 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.44
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJ99 NP_067071.1 828 89091 T680 E G G G E Q D T E A Y D M S A
Chimpanzee Pan troglodytes XP_525344 659 70856 E512 Y N D E G G G E Q D T E A Y D
Rhesus Macaque Macaca mulatta XP_001104171 835 89101 S687 D T E A Y D M S A L R S L Y D
Dog Lupus familis XP_543030 825 88615 E677 Y N D E G G G E Q D T E A Y D
Cat Felis silvestris
Mouse Mus musculus Q9WTP5 813 88003 I665 E D M R D N V I K Y N D E G G
Rat Rattus norvegicus Q63315 813 87960 I665 E D M R D N V I K Y N D E G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507828 874 96521 E727 E P L I I S E E D V R E N V V
Chicken Gallus gallus Q90763 785 87153 L638 R R R K K E P L I F D E E R D
Frog Xenopus laevis Q91838 790 88487 Y643 R R H R K Q P Y T I D E E D N
Zebra Danio Brachydanio rerio NP_001070916 787 86379 D640 G T S D L D E D R D V R E D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 76.8 88.5 96.6 N.A. 93 92.8 N.A. 49.6 53 49 50.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 77.7 92 97.8 N.A. 94.6 94.4 N.A. 66.3 70 66.6 67.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 0 0 N.A. 13.3 13.3 N.A. 6.6 0 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 20 13.3 N.A. 26.6 26.6 N.A. 26.6 20 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 10 10 0 0 20 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 20 20 10 20 20 10 10 10 30 20 30 0 20 40 % D
% Glu: 40 0 10 20 10 10 20 30 10 0 0 50 50 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 10 10 10 10 20 20 20 0 0 0 0 0 0 20 20 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 10 0 0 20 10 10 0 0 0 0 10 % I
% Lys: 0 0 0 10 20 0 0 0 20 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 10 0 0 10 0 10 0 0 10 0 0 % L
% Met: 0 0 20 0 0 0 10 0 0 0 0 0 10 0 0 % M
% Asn: 0 20 0 0 0 20 0 0 0 0 20 0 10 0 10 % N
% Pro: 0 10 0 0 0 0 20 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 20 0 0 20 0 0 0 0 0 0 % Q
% Arg: 20 20 10 30 0 0 0 0 10 0 20 10 0 10 0 % R
% Ser: 0 0 10 0 0 10 0 10 0 0 0 10 0 10 0 % S
% Thr: 0 20 0 0 0 0 0 10 10 0 20 0 0 0 0 % T
% Val: 0 0 0 0 0 0 20 0 0 10 10 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 20 0 0 0 10 0 0 10 0 20 10 0 0 30 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _