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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
22.73
Human Site:
S28
Identified Species:
31.25
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S28
G
R
G
G
G
N
F
S
G
K
W
R
E
R
E
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S28
G
R
G
G
G
N
F
S
G
K
W
R
E
R
E
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S28
G
K
G
G
G
N
F
S
G
K
W
R
E
R
G
Dog
Lupus familis
XP_534352
833
93150
T28
G
R
G
G
G
S
F
T
G
Q
W
R
E
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
S28
G
R
G
G
G
N
F
S
G
R
W
R
E
R
E
Rat
Rattus norvegicus
NP_001099984
830
91958
S28
G
R
G
G
G
N
F
S
G
R
W
R
D
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
G33
W
R
G
K
G
Q
K
G
D
W
N
K
N
K
D
Chicken
Gallus gallus
XP_001232579
830
92790
G26
W
R
G
G
W
R
G
G
W
R
G
G
W
R
G
Frog
Xenopus laevis
P55861
886
100243
L31
T
S
S
P
G
R
D
L
P
P
F
E
D
E
S
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
Y29
P
Y
K
G
W
R
L
Y
F
S
E
G
F
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
F35
P
V
G
D
F
E
P
F
E
N
E
D
E
I
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
L28
Q
N
E
F
S
K
F
L
K
S
F
K
D
Q
K
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
G29
S
W
N
N
R
G
R
G
G
G
F
G
N
N
V
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
Maize
Zea mays
Q43704
768
85163
Q21
A
F
L
D
F
L
D
Q
D
V
G
K
G
V
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
K28
S
M
Y
M
E
E
I
K
A
L
V
H
Q
K
R
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
F45
Q
I
G
S
R
L
H
F
P
S
S
S
Q
P
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
86.6
73.3
N.A.
93.3
80
N.A.
20
26.6
6.6
13.3
N.A.
13.3
N.A.
6.6
6.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
93.3
N.A.
40
33.3
20
13.3
N.A.
13.3
N.A.
40
13.3
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
0
0
N.A.
0
6.6
N.A.
P-Site Similarity:
0
6.6
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
0
12
0
12
0
0
6
18
0
6
% D
% Glu:
0
0
6
0
6
12
0
0
6
0
12
6
36
6
30
% E
% Phe:
0
6
0
6
12
0
42
12
6
0
18
0
6
0
0
% F
% Gly:
36
0
59
48
48
6
6
18
42
6
12
18
6
0
12
% G
% His:
0
0
0
0
0
0
6
0
0
0
0
6
0
0
6
% H
% Ile:
0
6
0
0
0
0
6
0
0
0
0
0
0
6
0
% I
% Lys:
0
6
6
6
0
6
6
6
6
18
0
18
0
18
6
% K
% Leu:
0
0
6
0
0
12
6
12
0
6
0
0
0
0
6
% L
% Met:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
6
6
0
30
0
0
0
6
6
0
12
6
0
% N
% Pro:
12
0
0
6
0
0
6
0
12
6
0
0
0
6
0
% P
% Gln:
12
0
0
0
0
6
0
6
0
6
0
0
12
6
0
% Q
% Arg:
0
42
0
0
12
18
6
0
0
18
0
36
0
36
6
% R
% Ser:
12
6
6
6
6
6
0
30
0
18
6
6
0
0
6
% S
% Thr:
6
0
0
0
0
0
0
6
0
0
0
0
0
0
6
% T
% Val:
0
6
0
0
0
0
0
0
0
6
6
0
0
12
6
% V
% Trp:
12
6
0
0
12
0
0
0
6
6
36
0
6
0
0
% W
% Tyr:
0
6
6
0
0
0
0
6
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _