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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
14.55
Human Site:
S361
Identified Species:
20
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S361
L
L
Y
I
E
A
N
S
I
S
N
S
K
G
Q
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S361
L
L
Y
I
E
A
N
S
I
S
N
S
K
G
Q
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S361
L
L
Y
I
E
A
N
S
I
S
N
S
K
G
Q
Dog
Lupus familis
XP_534352
833
93150
K359
A
N
S
V
S
N
S
K
G
Q
K
T
K
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
G360
N
S
V
S
N
S
K
G
P
K
A
Q
T
A
E
Rat
Rattus norvegicus
NP_001099984
830
91958
A360
S
N
S
K
G
Q
K
A
Q
T
A
E
D
G
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
G364
K
T
K
I
S
E
D
G
S
N
H
R
A
S
M
Chicken
Gallus gallus
XP_001232579
830
92790
T362
S
N
S
K
G
Q
K
T
K
N
F
E
E
E
T
Frog
Xenopus laevis
P55861
886
100243
K379
A
G
R
L
P
R
S
K
D
A
I
L
L
A
D
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
V368
V
I
Y
G
H
L
L
V
K
A
G
L
A
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
V429
T
V
I
I
A
N
H
V
V
V
K
D
S
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
G367
G
N
H
E
V
K
L
G
V
L
L
M
L
L
G
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
S361
L
L
Y
I
H
A
N
S
L
S
N
L
K
K
S
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
E329
S
F
S
P
R
D
L
E
F
I
V
K
F
S
E
Maize
Zea mays
Q43704
768
85163
A352
A
K
S
Q
L
L
R
A
V
M
N
I
A
P
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
G360
P
L
A
I
S
T
T
G
R
G
S
S
G
V
G
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
T430
T
R
G
I
S
K
T
T
E
G
L
N
S
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
6.6
N.A.
0
6.6
N.A.
6.6
0
0
6.6
N.A.
13.3
N.A.
0
66.6
P-Site Similarity:
100
100
100
26.6
N.A.
13.3
20
N.A.
26.6
20
20
26.6
N.A.
33.3
N.A.
13.3
73.3
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
0
6.6
N.A.
20
13.3
N.A.
P-Site Similarity:
6.6
20
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
0
6
0
6
24
0
12
0
12
12
0
18
12
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% C
% Asp:
0
0
0
0
0
6
6
0
6
0
0
6
6
0
6
% D
% Glu:
0
0
0
6
18
6
0
6
6
0
0
12
6
6
12
% E
% Phe:
0
6
0
0
0
0
0
0
6
0
6
0
6
0
0
% F
% Gly:
6
6
6
6
12
0
0
24
6
12
6
0
6
30
12
% G
% His:
0
0
6
0
12
0
6
0
0
0
6
0
0
0
0
% H
% Ile:
0
6
6
48
0
0
0
0
18
6
6
6
0
0
0
% I
% Lys:
6
6
6
12
0
12
18
12
12
6
12
6
30
12
0
% K
% Leu:
24
30
0
6
6
12
18
0
6
6
12
18
12
12
6
% L
% Met:
0
0
0
0
0
0
0
0
0
6
0
6
0
0
6
% M
% Asn:
6
24
0
0
6
12
24
0
0
12
30
6
0
0
0
% N
% Pro:
6
0
0
6
6
0
0
0
6
0
0
0
0
6
0
% P
% Gln:
0
0
0
6
0
12
0
0
6
6
0
6
0
0
24
% Q
% Arg:
0
6
6
0
6
6
6
0
6
0
0
6
0
0
0
% R
% Ser:
18
6
30
6
24
6
12
24
6
24
6
24
12
12
12
% S
% Thr:
12
6
0
0
0
6
12
12
0
6
0
6
6
6
6
% T
% Val:
6
6
6
6
6
0
0
12
18
6
6
0
0
6
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _