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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
23.94
Human Site:
S622
Identified Species:
32.92
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S622
G
K
Q
R
T
I
S
S
A
T
V
A
R
M
N
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S622
G
K
Q
R
T
I
S
S
A
T
V
A
R
M
N
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S622
G
K
Q
R
T
I
S
S
V
T
V
A
R
T
N
Dog
Lupus familis
XP_534352
833
93150
S615
G
K
Q
R
T
V
S
S
A
T
I
A
R
M
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
S615
G
K
Q
K
A
V
S
S
A
T
V
T
R
V
L
Rat
Rattus norvegicus
NP_001099984
830
91958
S612
G
K
Q
R
A
V
S
S
A
T
V
S
R
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
S610
G
K
S
K
I
I
Q
S
A
T
V
V
R
L
N
Chicken
Gallus gallus
XP_001232579
830
92790
C612
R
A
G
K
Q
A
V
C
S
S
A
V
V
S
R
Frog
Xenopus laevis
P55861
886
100243
D677
K
H
H
P
S
S
K
D
I
A
N
G
D
A
A
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
I583
F
N
T
H
E
S
S
I
S
I
L
E
V
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
E677
K
H
H
P
S
E
E
E
Q
P
E
L
E
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
K603
T
L
V
R
E
Y
K
K
L
R
M
S
D
S
N
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
R628
M
S
G
V
R
V
T
R
H
P
S
G
S
I
T
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
D542
D
K
P
D
E
V
L
D
K
R
V
S
D
H
I
Maize
Zea mays
Q43704
768
85163
A565
L
K
K
Y
I
H
Y
A
K
N
L
I
Q
P
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
A573
D
E
A
S
E
R
I
A
E
A
Y
A
D
L
R
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
P744
K
R
D
E
A
I
E
P
P
F
S
A
E
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
86.6
86.6
N.A.
60
66.6
N.A.
60
0
0
6.6
N.A.
0
N.A.
13.3
0
P-Site Similarity:
100
100
86.6
100
N.A.
80
86.6
N.A.
73.3
20
6.6
26.6
N.A.
6.6
N.A.
26.6
20
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
13.3
6.6
N.A.
6.6
13.3
N.A.
P-Site Similarity:
26.6
33.3
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
18
6
0
12
36
12
6
36
0
6
6
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% C
% Asp:
12
0
6
6
0
0
0
12
0
0
0
0
24
0
0
% D
% Glu:
0
6
0
6
24
6
12
6
6
0
6
6
12
6
0
% E
% Phe:
6
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% F
% Gly:
42
0
12
0
0
0
0
0
0
0
0
12
0
0
0
% G
% His:
0
12
12
6
0
6
0
0
6
0
0
0
0
6
0
% H
% Ile:
0
0
0
0
12
30
6
6
6
6
6
6
0
6
6
% I
% Lys:
18
53
6
18
0
0
12
6
12
0
0
0
0
0
0
% K
% Leu:
6
6
0
0
0
0
6
0
6
0
12
6
0
12
18
% L
% Met:
6
0
0
0
0
0
0
0
0
0
6
0
0
18
0
% M
% Asn:
0
6
0
0
0
0
0
0
0
6
6
0
0
0
36
% N
% Pro:
0
0
6
12
0
0
0
6
6
12
0
0
0
6
6
% P
% Gln:
0
0
36
0
6
0
6
0
6
0
0
0
6
6
0
% Q
% Arg:
6
6
0
36
6
6
0
6
0
12
0
0
42
0
18
% R
% Ser:
0
6
6
6
12
12
42
42
12
6
12
18
6
18
6
% S
% Thr:
6
0
6
0
24
0
6
0
0
42
0
6
0
6
6
% T
% Val:
0
0
6
6
0
30
6
0
6
0
42
12
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
0
6
6
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _