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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
9.7
Human Site:
S64
Identified Species:
13.33
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S64
L
S
T
K
T
P
Q
S
M
Q
S
T
L
D
R
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S64
L
S
T
K
T
P
Q
S
M
Q
S
T
L
D
R
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S64
L
S
T
K
T
P
Q
S
M
Q
S
T
L
D
Q
Dog
Lupus familis
XP_534352
833
93150
Q64
L
L
Q
S
T
L
D
Q
F
I
P
Y
K
G
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
Q64
L
Q
Q
S
T
L
D
Q
F
I
P
Y
K
G
W
Rat
Rattus norvegicus
NP_001099984
830
91958
P64
S
T
L
D
Q
F
I
P
Y
K
G
W
K
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
Y69
P
Y
K
G
W
K
L
Y
F
S
E
V
Y
S
D
Chicken
Gallus gallus
XP_001232579
830
92790
Y66
T
L
D
Q
F
I
P
Y
K
G
W
K
L
Y
F
Frog
Xenopus laevis
P55861
886
100243
R67
D
A
M
E
R
D
Y
R
P
I
S
E
L
D
R
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
R65
Y
D
K
D
E
I
E
R
K
G
S
I
L
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
M71
M
E
N
D
Y
R
P
M
P
E
L
D
H
Y
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
K64
I
N
M
Q
H
L
Y
K
F
S
N
N
L
A
T
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
R65
L
I
P
Y
K
G
W
R
L
Y
F
T
D
E
T
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
N34
L
A
T
Y
C
P
S
N
E
L
A
V
D
E
E
Maize
Zea mays
Q43704
768
85163
L57
L
R
N
H
N
L
D
L
A
R
R
V
I
R
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
M64
L
K
N
P
N
E
Y
M
Q
S
F
C
D
A
A
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
N81
Q
T
D
G
S
A
T
N
D
M
E
G
N
E
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
93.3
13.3
N.A.
13.3
0
N.A.
0
6.6
26.6
13.3
N.A.
0
N.A.
6.6
13.3
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
0
13.3
40
20
N.A.
13.3
N.A.
33.3
26.6
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
20
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
46.6
20
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
0
0
0
6
0
0
6
0
6
0
0
12
6
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
6
0
0
0
% C
% Asp:
6
6
12
18
0
6
18
0
6
0
0
6
18
24
18
% D
% Glu:
0
6
0
6
6
6
6
0
6
6
12
6
0
18
6
% E
% Phe:
0
0
0
0
6
6
0
0
24
0
12
0
0
0
6
% F
% Gly:
0
0
0
12
0
6
0
0
0
12
6
6
0
12
0
% G
% His:
0
0
0
6
6
0
0
0
0
0
0
0
6
0
0
% H
% Ile:
6
6
0
0
0
12
6
0
0
18
0
6
6
0
0
% I
% Lys:
0
6
12
18
6
6
0
6
12
6
0
6
18
0
0
% K
% Leu:
53
12
6
0
0
24
6
6
6
6
6
0
42
6
0
% L
% Met:
6
0
12
0
0
0
0
12
18
6
0
0
0
0
0
% M
% Asn:
0
6
18
0
12
0
0
12
0
0
6
6
6
0
0
% N
% Pro:
6
0
6
6
0
24
12
6
12
0
12
0
0
0
6
% P
% Gln:
6
6
12
12
6
0
18
12
6
18
0
0
0
0
6
% Q
% Arg:
0
6
0
0
6
6
0
18
0
6
6
0
0
6
18
% R
% Ser:
6
18
0
12
6
0
6
18
0
18
30
0
0
6
0
% S
% Thr:
6
12
24
0
30
0
6
0
0
0
0
24
0
0
18
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
18
0
6
0
% V
% Trp:
0
0
0
0
6
0
6
0
0
0
6
6
0
0
12
% W
% Tyr:
6
6
0
12
6
0
18
12
6
6
0
12
6
12
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _