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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
34.55
Human Site:
S642
Identified Species:
47.5
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S642
T
S
V
L
E
V
V
S
E
K
P
L
S
E
R
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S642
T
S
V
L
E
V
V
S
E
K
P
L
S
E
R
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S642
T
L
V
L
E
V
V
S
E
K
P
L
S
E
R
Dog
Lupus familis
XP_534352
833
93150
S635
T
S
V
L
E
V
V
S
D
K
P
L
S
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
S635
T
S
V
L
E
V
V
S
E
K
P
L
S
E
R
Rat
Rattus norvegicus
NP_001099984
830
91958
S632
T
S
V
L
E
V
V
S
E
K
P
L
S
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
S630
T
S
L
L
E
V
V
S
D
K
P
L
S
E
R
Chicken
Gallus gallus
XP_001232579
830
92790
S632
R
S
V
L
E
V
V
S
D
R
P
L
L
E
R
Frog
Xenopus laevis
P55861
886
100243
L697
N
T
F
G
V
E
A
L
P
Q
E
V
L
K
K
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
G603
D
T
L
K
L
V
P
G
E
A
F
D
P
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
L697
D
E
I
P
Q
D
L
L
R
Q
Y
I
V
Y
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
Q623
S
W
R
I
T
V
R
Q
L
E
S
L
V
R
L
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
S648
D
A
R
R
L
W
E
S
E
R
P
L
S
E
R
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
P562
D
F
A
P
L
P
G
P
L
L
R
K
Y
I
A
Maize
Zea mays
Q43704
768
85163
Y585
S
D
H
I
A
T
S
Y
A
E
L
R
D
G
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
P593
T
K
T
G
G
T
L
P
I
T
A
R
T
L
E
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
I764
Y
A
R
T
F
K
P
I
L
T
K
E
A
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
93.3
93.3
N.A.
100
100
N.A.
86.6
73.3
0
13.3
N.A.
0
N.A.
13.3
46.6
P-Site Similarity:
100
100
93.3
100
N.A.
100
100
N.A.
100
86.6
33.3
26.6
N.A.
33.3
N.A.
33.3
60
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
0
0
N.A.
6.6
0
N.A.
P-Site Similarity:
0
20
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
6
0
6
0
6
0
6
6
6
0
6
0
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
6
0
0
0
6
0
0
18
0
0
6
6
0
0
% D
% Glu:
0
6
0
0
48
6
6
0
42
12
6
6
0
53
6
% E
% Phe:
0
6
6
0
6
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
0
0
0
12
6
0
6
6
0
0
0
0
0
6
0
% G
% His:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
12
0
0
0
6
6
0
0
6
0
12
0
% I
% Lys:
0
6
0
6
0
6
0
0
0
42
6
6
0
6
6
% K
% Leu:
0
6
12
48
18
0
12
12
18
6
6
59
12
6
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
12
0
6
12
12
6
0
53
0
6
0
6
% P
% Gln:
0
0
0
0
6
0
0
6
0
12
0
0
0
0
0
% Q
% Arg:
6
0
18
6
0
0
6
0
6
12
6
12
0
12
53
% R
% Ser:
12
42
0
0
0
0
6
53
0
0
6
0
48
0
12
% S
% Thr:
48
12
6
6
6
12
0
0
0
12
0
0
6
0
0
% T
% Val:
0
0
42
0
6
59
48
0
0
0
0
6
12
0
0
% V
% Trp:
0
6
0
0
0
6
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
6
0
0
6
0
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _