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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
30.91
Human Site:
S647
Identified Species:
42.5
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S647
V
V
S
E
K
P
L
S
E
R
L
K
V
V
P
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S647
V
V
S
E
K
P
L
S
E
R
L
K
V
V
P
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S647
V
V
S
E
K
P
L
S
E
R
L
K
V
V
P
Dog
Lupus familis
XP_534352
833
93150
S640
V
V
S
D
K
P
L
S
E
R
L
K
V
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
S640
V
V
S
E
K
P
L
S
E
R
L
K
V
A
P
Rat
Rattus norvegicus
NP_001099984
830
91958
S637
V
V
S
E
K
P
L
S
E
R
L
K
V
A
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
S635
V
V
S
D
K
P
L
S
E
R
L
K
V
I
P
Chicken
Gallus gallus
XP_001232579
830
92790
L637
V
V
S
D
R
P
L
L
E
R
L
K
I
S
P
Frog
Xenopus laevis
P55861
886
100243
L702
E
A
L
P
Q
E
V
L
K
K
Y
I
M
Y
A
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
P608
V
P
G
E
A
F
D
P
I
P
H
Q
L
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
V702
D
L
L
R
Q
Y
I
V
Y
A
K
E
N
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
V628
V
R
Q
L
E
S
L
V
R
L
S
E
A
L
A
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
S653
W
E
S
E
R
P
L
S
E
R
L
K
V
G
R
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
Y567
P
G
P
L
L
R
K
Y
I
A
Y
A
R
T
Y
Maize
Zea mays
Q43704
768
85163
D590
T
S
Y
A
E
L
R
D
G
S
A
N
A
K
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
T598
T
L
P
I
T
A
R
T
L
E
T
I
I
R
L
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
A769
K
P
I
L
T
K
E
A
R
S
Y
L
V
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
66.6
0
13.3
N.A.
0
N.A.
13.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
100
86.6
33.3
33.3
N.A.
33.3
N.A.
33.3
73.3
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
0
0
N.A.
0
6.6
N.A.
P-Site Similarity:
0
6.6
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
6
6
6
0
6
0
12
6
6
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
18
0
0
6
6
0
0
0
0
0
0
0
% D
% Glu:
6
6
0
42
12
6
6
0
53
6
0
12
0
6
0
% E
% Phe:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
6
6
0
0
0
0
0
6
0
0
0
0
6
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% H
% Ile:
0
0
6
6
0
0
6
0
12
0
0
12
12
12
0
% I
% Lys:
6
0
0
0
42
6
6
0
6
6
6
53
0
6
6
% K
% Leu:
0
12
12
18
6
6
59
12
6
6
53
6
6
12
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
6
6
0
0
% N
% Pro:
6
12
12
6
0
53
0
6
0
6
0
0
0
0
48
% P
% Gln:
0
0
6
0
12
0
0
0
0
0
0
6
0
0
0
% Q
% Arg:
0
6
0
6
12
6
12
0
12
53
0
0
6
6
18
% R
% Ser:
0
6
53
0
0
6
0
48
0
12
6
0
0
6
6
% S
% Thr:
12
0
0
0
12
0
0
6
0
0
6
0
0
6
0
% T
% Val:
59
48
0
0
0
0
6
12
0
0
0
0
53
24
0
% V
% Trp:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
0
0
6
0
6
6
0
18
0
0
6
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _