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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
23.33
Human Site:
S700
Identified Species:
32.08
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S700
Y
L
E
L
R
K
Q
S
Q
R
L
N
S
S
P
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S700
Y
L
E
L
R
K
Q
S
Q
R
L
N
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S700
Y
L
E
L
R
K
Q
S
Q
R
L
N
S
S
P
Dog
Lupus familis
XP_534352
833
93150
S693
Y
L
E
L
R
K
Q
S
Q
R
L
N
S
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
S693
Y
L
E
L
R
K
Q
S
Q
R
V
G
S
S
P
Rat
Rattus norvegicus
NP_001099984
830
91958
S690
Y
L
E
L
R
K
Q
S
Q
R
V
G
S
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
N688
Y
L
E
L
R
K
Q
N
L
G
L
D
S
T
P
Chicken
Gallus gallus
XP_001232579
830
92790
N690
Y
L
E
L
R
K
Q
N
Q
G
A
S
S
T
P
Frog
Xenopus laevis
P55861
886
100243
M755
H
I
E
S
M
I
R
M
A
E
A
H
A
R
M
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
L661
T
P
I
T
T
R
Q
L
E
S
L
I
R
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
A755
I
R
M
S
E
A
H
A
R
M
H
L
R
E
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
V681
F
D
N
N
I
M
V
V
E
A
D
K
E
N
Q
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
H706
Y
L
E
L
R
R
Q
H
Q
G
M
D
S
T
L
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
A620
S
L
V
R
L
A
E
A
R
A
R
L
E
L
R
Maize
Zea mays
Q43704
768
85163
A643
A
L
Q
V
L
N
F
A
I
Y
H
K
E
L
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
Q651
D
R
E
Q
E
E
R
Q
R
E
Q
A
E
Q
E
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
S822
C
V
D
E
I
T
P
S
F
I
A
E
A
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
66.6
66.6
6.6
13.3
N.A.
0
N.A.
0
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
40
26.6
N.A.
13.3
N.A.
20
80
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
26.6
26.6
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
12
0
18
6
12
18
6
12
0
0
% A
% Cys:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
6
0
0
0
0
0
0
0
6
12
0
0
6
% D
% Glu:
0
0
65
6
12
6
6
0
12
12
0
6
24
6
6
% E
% Phe:
6
0
0
0
0
0
6
0
6
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
18
0
12
0
0
0
% G
% His:
6
0
0
0
0
0
6
6
0
0
12
6
0
0
0
% H
% Ile:
6
6
6
0
12
6
0
0
6
6
0
6
0
0
0
% I
% Lys:
0
0
0
0
0
48
0
0
0
0
0
12
0
0
0
% K
% Leu:
0
65
0
53
12
0
0
6
6
0
36
12
0
18
6
% L
% Met:
0
0
6
0
6
6
0
6
0
6
6
0
0
0
6
% M
% Asn:
0
0
6
6
0
6
0
12
0
0
0
24
0
6
6
% N
% Pro:
0
6
0
0
0
0
6
0
0
0
0
0
0
0
48
% P
% Gln:
0
0
6
6
0
0
59
6
48
0
6
0
0
6
6
% Q
% Arg:
0
12
0
6
53
12
12
0
18
36
6
0
12
6
6
% R
% Ser:
6
0
0
12
0
0
0
42
0
6
0
6
53
36
0
% S
% Thr:
6
0
0
6
6
6
0
0
0
0
0
0
0
18
12
% T
% Val:
0
6
6
6
0
0
6
6
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
53
0
0
0
0
0
0
0
0
6
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _