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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
36.36
Human Site:
S715
Identified Species:
50
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S715
I
T
T
R
Q
L
E
S
L
I
R
L
T
E
A
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S715
I
T
T
R
Q
L
E
S
L
I
R
L
T
E
A
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S715
I
T
T
R
Q
L
E
S
L
I
R
L
T
E
A
Dog
Lupus familis
XP_534352
833
93150
S708
I
T
T
R
Q
L
E
S
L
I
R
L
T
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
S708
I
T
T
R
Q
L
E
S
L
I
R
L
T
E
A
Rat
Rattus norvegicus
NP_001099984
830
91958
S705
I
T
T
R
Q
L
E
S
L
I
R
L
T
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
S703
I
T
T
R
Q
L
E
S
L
I
R
L
T
E
A
Chicken
Gallus gallus
XP_001232579
830
92790
S705
I
T
T
R
Q
L
E
S
L
I
R
L
T
E
A
Frog
Xenopus laevis
P55861
886
100243
E770
H
L
R
D
Y
V
V
E
D
D
V
N
M
A
I
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
L676
E
A
R
A
R
V
E
L
R
E
K
A
T
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
M770
V
M
E
A
D
V
S
M
A
I
R
M
M
L
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
H696
R
G
D
D
S
M
D
H
D
G
E
K
E
N
A
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
S721
I
T
T
R
Q
L
E
S
L
M
R
L
T
E
A
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
A635
E
E
V
T
A
Q
D
A
T
D
V
V
E
I
M
Maize
Zea mays
Q43704
768
85163
K658
E
M
E
E
R
E
Q
K
E
M
E
M
K
Q
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
G666
R
T
P
S
G
R
R
G
N
Q
R
R
N
N
E
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
R837
L
L
R
Q
S
I
I
R
V
D
V
D
D
V
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
0
13.3
N.A.
13.3
N.A.
6.6
93.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
6.6
46.6
N.A.
33.3
N.A.
20
100
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
0
0
N.A.
13.3
0
N.A.
P-Site Similarity:
20
33.3
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
12
6
0
0
6
6
0
0
6
0
6
59
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
12
6
0
12
0
12
18
0
6
6
0
0
% D
% Glu:
18
6
12
6
0
6
59
6
6
6
12
0
12
53
18
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
6
0
0
6
0
0
6
0
6
0
0
0
0
0
% G
% His:
6
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
53
0
0
0
0
6
6
0
0
53
0
0
0
6
6
% I
% Lys:
0
0
0
0
0
0
0
6
0
0
6
6
6
0
0
% K
% Leu:
6
12
0
0
0
53
0
6
53
0
0
53
0
6
0
% L
% Met:
0
12
0
0
0
6
0
6
0
12
0
12
12
0
6
% M
% Asn:
0
0
0
0
0
0
0
0
6
0
0
6
6
12
0
% N
% Pro:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
6
53
6
6
0
0
6
0
0
0
12
6
% Q
% Arg:
12
0
18
53
12
6
6
6
6
0
65
6
0
0
0
% R
% Ser:
0
0
0
6
12
0
6
53
0
0
0
0
0
0
6
% S
% Thr:
0
59
53
6
0
0
0
0
6
0
0
0
59
0
0
% T
% Val:
6
0
6
0
0
18
6
0
6
0
18
6
0
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _