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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
36.36
Human Site:
S753
Identified Species:
50
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S753
Y
S
M
L
G
T
Y
S
D
E
F
G
N
L
D
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S753
Y
S
M
L
G
T
Y
S
D
E
F
G
N
L
D
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S753
Y
S
M
L
G
T
Y
S
D
E
F
G
N
L
D
Dog
Lupus familis
XP_534352
833
93150
S746
Y
S
M
L
G
T
Y
S
D
E
F
G
K
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
S746
H
S
M
L
G
T
Y
S
D
E
F
G
N
L
D
Rat
Rattus norvegicus
NP_001099984
830
91958
S743
H
S
M
L
G
T
Y
S
D
E
F
G
N
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
T741
Y
S
M
L
G
T
Y
T
D
E
F
G
N
L
D
Chicken
Gallus gallus
XP_001232579
830
92790
S743
Y
S
M
L
G
T
Y
S
D
E
F
G
K
L
D
Frog
Xenopus laevis
P55861
886
100243
R808
A
R
Y
L
A
F
R
R
D
N
N
E
L
L
L
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
L714
L
D
F
D
R
S
Q
L
G
S
G
M
S
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
L808
F
Q
K
D
H
S
E
L
L
F
F
I
L
R
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
D734
L
H
M
R
S
D
E
D
N
Q
G
E
D
E
Y
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
S759
F
S
M
I
D
T
Y
S
D
Q
F
G
F
L
D
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
R673
S
Q
Q
K
E
A
K
R
F
L
S
A
L
N
R
Maize
Zea mays
Q43704
768
85163
D696
D
V
D
V
G
S
N
D
Q
N
V
S
A
E
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
T704
S
V
E
Q
F
S
G
T
V
S
A
A
R
I
E
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
I875
D
G
T
G
S
G
V
I
T
S
E
P
P
A
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
20
0
N.A.
6.6
N.A.
6.6
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
93.3
20
13.3
N.A.
20
N.A.
26.6
86.6
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
0
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
0
20
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
6
6
0
0
0
0
6
12
6
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
6
6
12
6
6
0
12
59
0
0
0
6
0
59
% D
% Glu:
0
0
6
0
6
0
12
0
0
48
6
12
0
12
6
% E
% Phe:
12
0
6
0
6
6
0
0
6
6
59
0
6
0
0
% F
% Gly:
0
6
0
6
53
6
6
0
6
0
12
53
0
0
0
% G
% His:
12
6
0
0
6
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
0
0
0
6
0
0
0
6
0
6
0
% I
% Lys:
0
0
6
6
0
0
6
0
0
0
0
0
12
0
0
% K
% Leu:
12
0
0
53
0
0
0
12
6
6
0
0
18
59
6
% L
% Met:
0
0
59
0
0
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
0
0
0
0
0
0
6
0
6
12
6
0
36
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
6
6
0
0
% P
% Gln:
0
12
6
6
0
0
6
0
6
12
0
0
0
0
6
% Q
% Arg:
0
6
0
6
6
0
6
12
0
0
0
0
6
6
18
% R
% Ser:
12
53
0
0
12
24
0
48
0
18
6
6
6
0
0
% S
% Thr:
0
0
6
0
0
53
0
12
6
0
0
0
0
0
0
% T
% Val:
0
12
0
6
0
0
6
0
6
0
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
36
0
6
0
0
0
53
0
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _