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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
38.48
Human Site:
S774
Identified Species:
52.92
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S774
G
S
G
M
S
N
R
S
T
A
K
R
F
I
S
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S774
G
S
G
M
S
N
R
S
T
A
K
R
F
I
S
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S774
G
S
G
M
S
N
R
S
T
A
K
R
F
I
S
Dog
Lupus familis
XP_534352
833
93150
S767
G
S
G
M
S
N
R
S
T
A
K
R
F
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
S767
G
S
G
M
S
N
R
S
T
A
K
R
F
I
S
Rat
Rattus norvegicus
NP_001099984
830
91958
S764
G
S
G
M
S
N
R
S
T
A
K
R
F
I
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
S762
G
S
G
M
S
N
R
S
L
A
K
R
F
I
S
Chicken
Gallus gallus
XP_001232579
830
92790
S764
G
S
G
M
S
N
R
S
Q
A
K
R
F
V
S
Frog
Xenopus laevis
P55861
886
100243
Q829
I
A
E
Q
V
T
Y
Q
R
N
R
Y
G
A
Q
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
A735
V
S
A
L
N
K
L
A
E
R
T
S
K
S
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
G829
A
Y
I
R
C
K
D
G
P
G
A
T
H
V
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
S755
A
L
V
E
W
Y
L
S
T
I
E
A
D
L
E
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
S780
G
S
G
M
S
S
K
S
L
A
K
R
F
V
A
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
E694
K
D
T
F
S
I
S
E
I
Y
S
L
A
D
R
Maize
Zea mays
Q43704
768
85163
A717
L
L
G
Q
H
V
L
A
N
H
I
D
Q
M
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
R725
G
Q
H
M
R
T
H
R
L
D
D
I
S
I
A
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
T896
E
A
T
A
R
P
G
T
S
E
K
K
K
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
86.6
0
6.6
N.A.
0
N.A.
13.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
93.3
13.3
26.6
N.A.
6.6
N.A.
26.6
93.3
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
6.6
13.3
N.A.
20
6.6
N.A.
P-Site Similarity:
6.6
26.6
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
6
6
0
0
0
12
0
53
6
6
6
6
12
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
0
0
0
0
6
0
0
6
6
6
6
6
0
% D
% Glu:
6
0
6
6
0
0
0
6
6
6
6
0
0
0
12
% E
% Phe:
0
0
0
6
0
0
0
0
0
0
0
0
53
0
0
% F
% Gly:
59
0
59
0
0
0
6
6
0
6
0
0
6
0
0
% G
% His:
0
0
6
0
6
0
6
0
0
6
0
0
6
0
0
% H
% Ile:
6
0
6
0
0
6
0
0
6
6
6
6
0
48
0
% I
% Lys:
6
0
0
0
0
12
6
0
0
0
59
6
12
0
0
% K
% Leu:
6
12
0
6
0
0
18
0
18
0
0
6
0
6
0
% L
% Met:
0
0
0
59
0
0
0
0
0
0
0
0
0
6
6
% M
% Asn:
0
0
0
0
6
48
0
0
6
6
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
6
0
0
6
0
0
0
0
0
0
% P
% Gln:
0
6
0
12
0
0
0
6
6
0
0
0
6
0
6
% Q
% Arg:
0
0
0
6
12
0
48
6
6
6
6
53
0
0
6
% R
% Ser:
0
59
0
0
59
6
6
59
6
0
6
6
6
6
53
% S
% Thr:
0
0
12
0
0
12
0
6
42
0
6
6
0
6
6
% T
% Val:
6
0
6
0
6
6
0
0
0
0
0
0
0
18
0
% V
% Trp:
0
0
0
0
6
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
0
0
6
6
0
0
6
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _