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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
10.3
Human Site:
S89
Identified Species:
14.17
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
S89
F
S
E
V
Y
S
D
S
S
P
L
I
E
K
I
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
S89
F
S
E
V
Y
S
D
S
S
P
L
V
E
K
I
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
S89
F
S
E
V
Y
S
D
S
S
P
L
I
E
K
I
Dog
Lupus familis
XP_534352
833
93150
I89
S
S
P
F
I
Q
K
I
Q
A
F
E
N
F
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
I89
N
S
P
F
I
E
K
I
Q
A
F
E
K
F
F
Rat
Rattus norvegicus
NP_001099984
830
91958
F89
L
T
E
K
I
Q
A
F
E
K
F
F
T
R
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
R94
F
E
K
F
F
I
Q
R
I
D
L
Y
D
K
D
Chicken
Gallus gallus
XP_001232579
830
92790
E91
V
Q
K
T
Q
A
F
E
K
F
F
M
Q
R
I
Frog
Xenopus laevis
P55861
886
100243
S92
D
V
E
D
L
T
A
S
Q
R
E
A
A
E
Q
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
A90
S
H
S
L
P
D
L
A
R
D
L
K
E
M
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
R96
S
E
M
S
Q
G
D
R
F
A
A
E
S
E
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
H89
P
F
M
C
E
A
L
H
L
A
T
L
D
A
C
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
F90
I
E
T
F
E
M
L
F
R
P
R
L
P
K
Y
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
G59
F
F
S
N
T
P
P
G
E
D
L
A
S
Q
V
Maize
Zea mays
Q43704
768
85163
N82
A
V
S
E
V
A
R
N
L
D
P
K
F
L
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
V89
Y
L
K
E
G
E
L
V
L
V
G
F
E
G
Y
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
V106
H
V
K
K
V
D
D
V
T
G
E
K
V
R
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
93.3
100
6.6
N.A.
6.6
6.6
N.A.
20
6.6
13.3
13.3
N.A.
6.6
N.A.
0
13.3
P-Site Similarity:
100
100
100
6.6
N.A.
13.3
20
N.A.
40
40
26.6
26.6
N.A.
20
N.A.
20
20
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
13.3
0
N.A.
6.6
6.6
N.A.
P-Site Similarity:
26.6
13.3
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
18
12
6
0
24
6
12
6
6
0
% A
% Cys:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
6
% C
% Asp:
6
0
0
6
0
12
30
0
0
24
0
0
12
0
6
% D
% Glu:
0
18
30
12
12
12
0
6
12
0
12
18
30
12
6
% E
% Phe:
30
12
0
24
6
0
6
12
6
6
24
12
6
12
12
% F
% Gly:
0
0
0
0
6
6
0
6
0
6
6
0
0
6
0
% G
% His:
6
6
0
0
0
0
0
6
0
0
0
0
0
0
6
% H
% Ile:
6
0
0
0
18
6
0
12
6
0
0
12
0
0
24
% I
% Lys:
0
0
24
12
0
0
12
0
6
6
0
18
6
30
6
% K
% Leu:
6
6
0
6
6
0
24
0
18
0
36
12
0
6
0
% L
% Met:
0
0
12
0
0
6
0
0
0
0
0
6
0
6
6
% M
% Asn:
6
0
0
6
0
0
0
6
0
0
0
0
6
0
0
% N
% Pro:
6
0
12
0
6
6
6
0
0
24
6
0
6
0
6
% P
% Gln:
0
6
0
0
12
12
6
0
18
0
0
0
6
6
6
% Q
% Arg:
0
0
0
0
0
0
6
12
12
6
6
0
0
18
0
% R
% Ser:
18
30
18
6
0
18
0
24
18
0
0
0
12
0
0
% S
% Thr:
0
6
6
6
6
6
0
0
6
0
6
0
6
0
0
% T
% Val:
6
18
0
18
12
0
0
12
0
6
0
6
6
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
18
0
0
0
0
0
0
6
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _