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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
15.45
Human Site:
T43
Identified Species:
21.25
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
T43
H
R
P
D
L
S
K
T
T
G
K
R
T
S
E
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
T43
H
R
P
D
L
S
K
T
T
G
K
R
T
S
E
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
T43
H
R
P
D
L
S
K
T
T
G
K
H
T
S
E
Dog
Lupus familis
XP_534352
833
93150
T43
H
R
S
D
L
N
K
T
M
R
K
H
T
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
A43
N
R
V
D
L
N
E
A
S
G
K
H
A
S
A
Rat
Rattus norvegicus
NP_001099984
830
91958
N43
D
L
S
K
A
A
G
N
H
A
S
E
Q
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
S48
T
H
D
S
G
P
S
S
Q
P
R
L
L
Q
S
Chicken
Gallus gallus
XP_001232579
830
92790
K45
R
T
Q
K
V
E
W
K
R
A
P
E
P
A
S
Frog
Xenopus laevis
P55861
886
100243
V46
E
G
M
F
G
D
G
V
V
P
E
E
E
E
D
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
I44
S
S
P
Y
V
E
K
I
K
V
F
E
Q
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
E50
G
D
Q
T
V
R
D
E
A
E
E
E
D
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
A43
N
E
F
I
Y
K
S
A
M
K
E
L
V
Q
P
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
S44
S
S
N
A
T
T
V
S
S
T
R
H
I
E
M
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
K13
G
E
S
A
S
R
K
K
Q
H
H
H
Y
A
S
Maize
Zea mays
Q43704
768
85163
V36
M
Q
A
V
R
D
M
V
Q
N
K
R
H
R
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
S43
H
R
L
I
I
N
I
S
D
I
H
H
H
F
R
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
P60
V
S
N
S
Q
T
G
P
F
V
N
D
S
T
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
93.3
66.6
N.A.
40
0
N.A.
0
0
0
13.3
N.A.
6.6
N.A.
0
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
66.6
13.3
N.A.
13.3
13.3
13.3
20
N.A.
20
N.A.
13.3
26.6
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
6.6
13.3
N.A.
13.3
0
N.A.
P-Site Similarity:
13.3
20
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
12
6
6
0
12
6
12
0
0
6
18
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
6
30
0
12
6
0
6
0
0
6
6
0
6
% D
% Glu:
6
12
0
0
0
12
6
6
0
6
18
30
6
12
30
% E
% Phe:
0
0
6
6
0
0
0
0
6
0
6
0
0
6
6
% F
% Gly:
12
6
0
0
12
0
18
0
0
24
0
0
0
6
0
% G
% His:
30
6
0
0
0
0
0
0
6
6
12
36
12
0
0
% H
% Ile:
0
0
0
12
6
0
6
6
0
6
0
0
6
0
0
% I
% Lys:
0
0
0
12
0
6
36
12
6
6
36
0
0
0
0
% K
% Leu:
0
6
6
0
30
0
0
0
0
0
0
12
6
0
6
% L
% Met:
6
0
6
0
0
0
6
0
12
0
0
0
0
0
6
% M
% Asn:
12
0
12
0
0
18
0
6
0
6
6
0
0
0
0
% N
% Pro:
0
0
24
0
0
6
0
6
0
12
6
0
6
0
6
% P
% Gln:
0
6
12
0
6
0
0
0
18
0
0
0
12
12
6
% Q
% Arg:
6
36
0
0
6
12
0
0
6
6
12
18
0
6
6
% R
% Ser:
12
18
18
12
6
18
12
18
12
0
6
0
6
30
24
% S
% Thr:
6
6
0
6
6
12
0
24
18
6
0
0
24
6
0
% T
% Val:
6
0
6
6
18
0
6
12
6
12
0
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
6
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
6
0
0
0
0
0
0
0
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _