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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
45.76
Human Site:
T490
Identified Species:
62.92
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
T490
T
T
S
G
L
T
V
T
L
S
K
D
S
S
S
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
T490
T
T
S
G
L
T
V
T
L
S
K
D
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
T490
T
T
S
G
L
T
V
T
L
S
K
D
S
S
S
Dog
Lupus familis
XP_534352
833
93150
T483
T
T
S
G
L
T
V
T
L
S
K
D
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
T483
T
S
S
G
L
T
V
T
L
S
K
D
S
S
S
Rat
Rattus norvegicus
NP_001099984
830
91958
T480
T
S
S
G
L
T
V
T
L
S
K
D
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
T478
T
T
S
G
L
T
V
T
L
S
R
D
S
T
S
Chicken
Gallus gallus
XP_001232579
830
92790
T482
T
S
S
G
L
T
V
T
L
S
R
D
G
A
S
Frog
Xenopus laevis
P55861
886
100243
Y544
S
A
V
G
L
T
A
Y
V
Q
R
H
P
V
T
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
A477
K
M
G
S
Q
H
Q
A
L
L
E
A
M
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
Y544
S
A
V
G
L
T
A
Y
V
R
R
N
P
V
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
T493
T
K
A
G
V
K
A
T
L
N
A
R
A
S
I
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
T491
T
T
S
G
L
T
V
T
L
T
K
D
G
S
S
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
K436
V
A
V
V
K
D
A
K
T
S
D
Y
A
F
E
Maize
Zea mays
Q43704
768
85163
T459
G
T
Y
D
R
S
L
T
P
T
K
N
I
G
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
S467
G
L
P
D
S
L
L
S
R
F
D
L
L
F
I
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
A611
S
A
A
G
L
T
A
A
V
V
R
D
E
E
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
73.3
20
6.6
N.A.
26.6
N.A.
33.3
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
46.6
13.3
N.A.
53.3
N.A.
60
93.3
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
6.6
20
N.A.
0
26.6
N.A.
P-Site Similarity:
13.3
46.6
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
12
0
0
0
30
12
0
0
6
6
12
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
12
0
6
0
0
0
0
12
59
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
6
0
6
12
6
% E
% Phe:
0
0
0
0
0
0
0
0
0
6
0
0
0
12
0
% F
% Gly:
12
0
6
77
0
0
0
0
0
0
0
0
12
6
6
% G
% His:
0
0
0
0
0
6
0
0
0
0
0
6
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
12
% I
% Lys:
6
6
0
0
6
6
0
6
0
0
48
0
0
0
0
% K
% Leu:
0
6
0
0
71
6
12
0
65
6
0
6
6
0
6
% L
% Met:
0
6
0
0
0
0
0
0
0
0
0
0
6
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
6
0
12
0
0
0
% N
% Pro:
0
0
6
0
0
0
0
0
6
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
6
0
6
0
0
6
0
0
0
0
6
% Q
% Arg:
0
0
0
0
6
0
0
0
6
6
30
6
0
0
0
% R
% Ser:
18
18
53
6
6
6
0
6
0
53
0
0
42
48
59
% S
% Thr:
59
42
0
0
0
71
0
65
6
12
0
0
0
6
6
% T
% Val:
6
0
18
6
6
0
53
0
18
6
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
6
0
0
0
0
12
0
0
0
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _