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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
13.64
Human Site:
T52
Identified Species:
18.75
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
T52
G
K
R
T
S
E
Q
T
P
Q
F
L
L
S
T
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
T52
G
K
R
T
S
E
Q
T
P
Q
F
L
L
S
T
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
T52
G
K
H
T
S
E
Q
T
P
Q
S
L
L
S
T
Dog
Lupus familis
XP_534352
833
93150
T52
R
K
H
T
S
E
Q
T
S
Q
S
S
L
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
A52
G
K
H
A
S
A
Q
A
S
Q
P
L
L
Q
Q
Rat
Rattus norvegicus
NP_001099984
830
91958
P52
A
S
E
Q
A
S
Q
P
L
L
Q
Q
S
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
L57
P
R
L
L
Q
S
T
L
D
Q
F
I
P
Y
K
Chicken
Gallus gallus
XP_001232579
830
92790
R54
A
P
E
P
A
S
S
R
L
V
Q
S
T
L
D
Frog
Xenopus laevis
P55861
886
100243
E55
P
E
E
E
E
D
G
E
E
L
I
G
D
A
M
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
S53
V
F
E
Q
Y
F
T
S
Q
I
D
L
Y
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
L59
E
E
E
D
G
E
E
L
F
G
D
N
M
E
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
K52
K
E
L
V
Q
P
E
K
N
T
I
F
I
N
M
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
N53
T
R
H
I
E
M
E
N
I
A
N
S
L
I
P
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
D22
H
H
H
Y
A
S
D
D
V
V
N
I
L
A
T
Maize
Zea mays
Q43704
768
85163
I45
N
K
R
H
R
L
I
I
G
M
D
D
L
R
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
V52
I
H
H
H
F
R
E
V
A
S
R
I
L
K
N
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
S69
V
N
D
S
T
Q
F
S
S
Q
R
L
Q
T
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
86.6
53.3
N.A.
46.6
6.6
N.A.
13.3
0
0
6.6
N.A.
6.6
N.A.
0
6.6
P-Site Similarity:
100
100
86.6
53.3
N.A.
46.6
20
N.A.
26.6
6.6
20
13.3
N.A.
26.6
N.A.
26.6
20
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
13.3
20
N.A.
6.6
13.3
N.A.
P-Site Similarity:
33.3
20
N.A.
20
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
6
18
6
0
6
6
6
0
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
6
0
6
6
6
6
0
18
6
6
6
12
% D
% Glu:
6
18
30
6
12
30
24
6
6
0
0
0
0
6
0
% E
% Phe:
0
6
0
0
6
6
6
0
6
0
18
6
0
0
0
% F
% Gly:
24
0
0
0
6
0
6
0
6
6
0
6
0
0
0
% G
% His:
6
12
36
12
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
0
6
0
0
6
6
6
6
12
18
6
6
0
% I
% Lys:
6
36
0
0
0
0
0
6
0
0
0
0
0
6
12
% K
% Leu:
0
0
12
6
0
6
0
12
12
12
0
36
53
12
6
% L
% Met:
0
0
0
0
0
6
0
0
0
6
0
0
6
0
12
% M
% Asn:
6
6
0
0
0
0
0
6
6
0
12
6
0
6
18
% N
% Pro:
12
6
0
6
0
6
0
6
18
0
6
0
6
0
6
% P
% Gln:
0
0
0
12
12
6
36
0
6
42
12
6
6
6
12
% Q
% Arg:
6
12
18
0
6
6
0
6
0
0
12
0
0
6
0
% R
% Ser:
0
6
0
6
30
24
6
12
18
6
12
18
6
18
0
% S
% Thr:
6
0
0
24
6
0
12
24
0
6
0
0
6
12
24
% T
% Val:
12
0
0
6
0
0
0
6
6
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
6
6
0
0
0
0
0
0
0
6
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _