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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
28.48
Human Site:
T596
Identified Species:
39.17
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
T596
L
V
F
I
L
L
D
T
P
N
E
H
H
D
H
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
T596
L
V
F
I
L
L
D
T
P
N
E
H
H
D
H
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
T596
L
V
F
I
L
L
D
T
P
N
E
H
H
D
H
Dog
Lupus familis
XP_534352
833
93150
T589
L
V
F
I
L
L
D
T
P
N
E
D
H
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
T589
L
V
F
I
L
L
D
T
P
N
E
Q
H
D
H
Rat
Rattus norvegicus
NP_001099984
830
91958
T586
L
V
F
I
L
L
D
T
P
N
E
Q
H
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
T584
L
V
F
I
L
L
D
T
P
N
E
D
H
D
H
Chicken
Gallus gallus
XP_001232579
830
92790
L586
F
D
L
V
F
I
L
L
D
T
P
N
E
D
H
Frog
Xenopus laevis
P55861
886
100243
T651
I
L
C
V
V
R
D
T
V
D
P
V
Q
D
E
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
V557
D
H
L
L
S
E
H
V
M
A
M
R
A
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
E651
V
L
C
V
V
K
D
E
F
D
P
M
Q
D
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
K577
Y
K
I
D
D
I
K
K
Y
I
A
F
A
R
C
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
M602
L
D
K
P
D
E
E
M
D
S
L
L
S
E
H
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
N516
R
A
K
T
V
N
E
N
L
K
M
S
A
A
L
Maize
Zea mays
Q43704
768
85163
G539
K
Y
D
R
M
L
H
G
Q
D
R
R
R
G
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
K547
H
D
K
T
L
T
I
K
F
L
K
K
Y
I
H
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
D718
L
F
F
V
I
L
D
D
C
N
E
K
I
D
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
13.3
20
0
N.A.
13.3
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
33.3
53.3
6.6
N.A.
46.6
N.A.
6.6
33.3
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
0
6.6
N.A.
13.3
46.6
N.A.
P-Site Similarity:
13.3
20
N.A.
26.6
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
0
0
0
0
6
6
0
18
6
0
% A
% Cys:
0
0
12
0
0
0
0
0
6
0
0
0
0
0
6
% C
% Asp:
6
18
6
6
12
0
59
6
12
18
0
12
0
65
0
% D
% Glu:
0
0
0
0
0
12
12
6
0
0
48
0
6
6
6
% E
% Phe:
6
6
48
0
6
0
0
0
12
0
0
6
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
6
0
0
0
0
0
12
0
% G
% His:
6
6
0
0
0
0
12
0
0
0
0
18
42
0
59
% H
% Ile:
6
0
6
42
6
12
6
0
0
6
0
0
6
6
0
% I
% Lys:
6
6
18
0
0
6
6
12
0
6
6
12
0
0
12
% K
% Leu:
53
12
12
6
48
53
6
6
6
6
6
6
0
0
6
% L
% Met:
0
0
0
0
6
0
0
6
6
0
12
6
0
0
0
% M
% Asn:
0
0
0
0
0
6
0
6
0
48
0
6
0
0
0
% N
% Pro:
0
0
0
6
0
0
0
0
42
0
18
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
6
0
0
12
12
0
6
% Q
% Arg:
6
0
0
6
0
6
0
0
0
0
6
12
6
6
0
% R
% Ser:
0
0
0
0
6
0
0
0
0
6
0
6
6
0
0
% S
% Thr:
0
0
0
12
0
6
0
48
0
6
0
0
0
0
6
% T
% Val:
6
42
0
24
18
0
0
6
6
0
0
6
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
6
0
0
0
0
0
0
6
0
0
0
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _