KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
17.58
Human Site:
T683
Identified Species:
24.17
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
T683
Y
V
Y
P
R
L
S
T
E
A
A
R
V
L
Q
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
T683
Y
V
Y
P
R
L
S
T
E
A
A
Q
V
L
Q
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
K683
Y
V
Y
P
R
L
S
K
E
A
A
Q
V
L
Q
Dog
Lupus familis
XP_534352
833
93150
T676
Y
V
Y
P
R
L
S
T
E
A
A
Q
I
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
T676
Y
V
H
P
R
L
S
T
D
A
A
Q
A
L
Q
Rat
Rattus norvegicus
NP_001099984
830
91958
T673
Y
V
H
P
R
L
S
T
E
A
A
Q
A
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
P671
Y
V
H
P
R
L
S
P
E
A
A
Q
A
L
Q
Chicken
Gallus gallus
XP_001232579
830
92790
P673
Y
V
H
P
H
L
S
P
E
A
A
Q
V
L
Q
Frog
Xenopus laevis
P55861
886
100243
A738
D
L
R
K
E
S
M
A
T
G
S
I
P
I
T
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
L644
L
Q
D
F
Y
L
E
L
R
K
Q
N
Q
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
P738
S
F
A
T
G
S
L
P
I
T
V
R
H
I
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
Q664
K
S
I
V
R
V
E
Q
P
D
I
A
L
D
D
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
P689
Y
V
Y
P
K
L
M
P
E
A
A
T
V
L
Q
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
C603
D
H
N
T
S
A
D
C
T
P
I
T
A
R
Q
Maize
Zea mays
Q43704
768
85163
H626
H
A
K
M
K
L
R
H
E
V
L
K
S
D
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
I634
L
K
L
M
N
F
A
I
Y
H
Q
E
L
T
E
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
R805
R
Q
L
E
S
M
I
R
L
S
E
A
I
A
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
93.3
86.6
86.6
N.A.
73.3
80
N.A.
73.3
73.3
0
6.6
N.A.
6.6
N.A.
6.6
73.3
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
86.6
86.6
20
6.6
N.A.
20
N.A.
20
80
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
6.6
13.3
N.A.
0
0
N.A.
P-Site Similarity:
6.6
33.3
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
6
0
0
6
6
6
0
53
53
12
24
6
6
% A
% Cys:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% C
% Asp:
12
0
6
0
0
0
6
0
6
6
0
0
0
12
6
% D
% Glu:
0
0
0
6
6
0
12
0
53
0
6
6
0
0
12
% E
% Phe:
0
6
0
6
0
6
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
6
0
0
0
0
6
0
0
0
0
0
% G
% His:
6
6
24
0
6
0
0
6
0
6
0
0
6
0
0
% H
% Ile:
0
0
6
0
0
0
6
6
6
0
12
6
12
12
0
% I
% Lys:
6
6
6
6
12
0
0
6
0
6
0
6
0
0
0
% K
% Leu:
12
6
12
0
0
65
6
6
6
0
6
0
12
53
0
% L
% Met:
0
0
0
12
0
6
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
6
0
6
0
0
0
0
0
0
6
0
0
0
% N
% Pro:
0
0
0
53
0
0
0
24
6
6
0
0
6
0
0
% P
% Gln:
0
12
0
0
0
0
0
6
0
0
12
42
6
0
59
% Q
% Arg:
6
0
6
0
48
0
6
6
6
0
0
12
0
6
6
% R
% Ser:
6
6
0
0
12
12
48
0
0
6
6
0
6
0
0
% S
% Thr:
0
0
0
12
0
0
0
30
12
6
0
12
0
12
6
% T
% Val:
0
53
0
6
0
6
0
0
0
6
6
0
30
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
53
0
30
0
6
0
0
0
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _