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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM8 All Species: 35.15
Human Site: T710 Identified Species: 48.33
UniProt: Q9UJA3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJA3 NP_115874.3 840 93697 T710 L N S S P I T T R Q L E S L I
Chimpanzee Pan troglodytes XP_001166964 840 93670 T710 L N S S P I T T R Q L E S L I
Rhesus Macaque Macaca mulatta XP_001115843 840 93650 T710 L N S S P I T T R Q L E S L I
Dog Lupus familis XP_534352 833 93150 T703 L N S S P I T T R Q L E S L I
Cat Felis silvestris
Mouse Mus musculus Q9CWV1 833 92353 T703 V G S S P I T T R Q L E S L I
Rat Rattus norvegicus NP_001099984 830 91958 T700 V G S S P I T T R Q L E S L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514432 828 92086 T698 L D S T P I T T R Q L E S L I
Chicken Gallus gallus XP_001232579 830 92790 T700 A S S T P I T T R Q L E S L I
Frog Xenopus laevis P55861 886 100243 R765 A H A R M H L R D Y V V E D D
Zebra Danio Brachydanio rerio XP_002665161 788 87122 R671 L I R L T E A R A R V E L R E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49735 887 100396 E765 H L R E N V M E A D V S M A I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34647 810 91112 D691 D K E N Q R G D D S M D H D G
Sea Urchin Strong. purpuratus XP_797782 848 93611 T716 M D S T L I T T R Q L E S L M
Poplar Tree Populus trichocarpa XP_002326332 745 82557 V630 R L E L R E E V T A Q D A T D
Maize Zea mays Q43704 768 85163 E653 H K E L T E M E E R E Q K E M
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL33 776 86338 P661 Q A E Q E R T P S G R R G N Q
Baker's Yeast Sacchar. cerevisiae P53091 1017 112934 R832 A E A Y D L L R Q S I I R V D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97 92.2 N.A. 89.2 89.7 N.A. 82.9 77.8 28.6 68.9 N.A. 25.8 N.A. 24.2 64.5
Protein Similarity: 100 99.8 98 95.8 N.A. 94.4 94 N.A. 90.5 87.2 47.2 80.8 N.A. 44.7 N.A. 43.6 77.1
P-Site Identity: 100 100 100 100 N.A. 86.6 86.6 N.A. 86.6 80 0 13.3 N.A. 6.6 N.A. 0 66.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 93.3 20 26.6 N.A. 20 N.A. 20 93.3
Percent
Protein Identity: 43.4 27.1 N.A. 27.7 25 N.A.
Protein Similarity: 61.3 48.6 N.A. 48.6 42.9 N.A.
P-Site Identity: 0 0 N.A. 6.6 0 N.A.
P-Site Similarity: 13.3 20 N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 18 6 12 0 0 0 6 0 12 6 0 0 6 6 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 12 0 0 6 0 0 6 12 6 0 12 0 12 18 % D
% Glu: 0 6 24 6 6 18 6 12 6 0 6 59 6 6 6 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 0 0 0 6 0 0 6 0 0 6 0 6 % G
% His: 12 6 0 0 0 6 0 0 0 0 0 0 6 0 0 % H
% Ile: 0 6 0 0 0 53 0 0 0 0 6 6 0 0 53 % I
% Lys: 0 12 0 0 0 0 0 0 0 0 0 0 6 0 0 % K
% Leu: 36 12 0 18 6 6 12 0 0 0 53 0 6 53 0 % L
% Met: 6 0 0 0 6 0 12 0 0 0 6 0 6 0 12 % M
% Asn: 0 24 0 6 6 0 0 0 0 0 0 0 0 6 0 % N
% Pro: 0 0 0 0 48 0 0 6 0 0 0 0 0 0 0 % P
% Gln: 6 0 0 6 6 0 0 0 6 53 6 6 0 0 6 % Q
% Arg: 6 0 12 6 6 12 0 18 53 12 6 6 6 6 0 % R
% Ser: 0 6 53 36 0 0 0 0 6 12 0 6 53 0 0 % S
% Thr: 0 0 0 18 12 0 59 53 6 0 0 0 0 6 0 % T
% Val: 12 0 0 0 0 6 0 6 0 0 18 6 0 6 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 0 0 0 6 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _