KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
38.79
Human Site:
T751
Identified Species:
53.33
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
T751
M
K
Y
S
M
L
G
T
Y
S
D
E
F
G
N
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
T751
M
K
Y
S
M
L
G
T
Y
S
D
E
F
G
N
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
T751
M
K
Y
S
M
L
G
T
Y
S
D
E
F
G
N
Dog
Lupus familis
XP_534352
833
93150
T744
M
K
Y
S
M
L
G
T
Y
S
D
E
F
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
T744
M
K
H
S
M
L
G
T
Y
S
D
E
F
G
N
Rat
Rattus norvegicus
NP_001099984
830
91958
T741
M
K
H
S
M
L
G
T
Y
S
D
E
F
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
T739
M
K
Y
S
M
L
G
T
Y
T
D
E
F
G
N
Chicken
Gallus gallus
XP_001232579
830
92790
T741
M
K
Y
S
M
L
G
T
Y
S
D
E
F
G
K
Frog
Xenopus laevis
P55861
886
100243
F806
T
F
A
R
Y
L
A
F
R
R
D
N
N
E
L
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
S712
G
R
L
D
F
D
R
S
Q
L
G
S
G
M
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
S806
L
S
F
Q
K
D
H
S
E
L
L
F
F
I
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
D732
L
V
L
H
M
R
S
D
E
D
N
Q
G
E
D
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
T757
M
K
F
S
M
I
D
T
Y
S
D
Q
F
G
F
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
A671
G
M
S
Q
Q
K
E
A
K
R
F
L
S
A
L
Maize
Zea mays
Q43704
768
85163
S694
P
M
D
V
D
V
G
S
N
D
Q
N
V
S
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
S702
E
P
S
V
E
Q
F
S
G
T
V
S
A
A
R
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
G873
N
D
D
G
T
G
S
G
V
I
T
S
E
P
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
13.3
0
N.A.
6.6
N.A.
6.6
66.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
93.3
13.3
20
N.A.
26.6
N.A.
33.3
86.6
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
0
6.6
N.A.
0
0
N.A.
P-Site Similarity:
0
20
N.A.
13.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
6
0
0
0
6
6
0
0
0
0
6
12
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
6
12
6
6
12
6
6
0
12
59
0
0
0
6
% D
% Glu:
6
0
0
0
6
0
6
0
12
0
0
48
6
12
0
% E
% Phe:
0
6
12
0
6
0
6
6
0
0
6
6
59
0
6
% F
% Gly:
12
0
0
6
0
6
53
6
6
0
6
0
12
53
0
% G
% His:
0
0
12
6
0
0
6
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
6
0
0
0
6
0
0
0
6
0
% I
% Lys:
0
53
0
0
6
6
0
0
6
0
0
0
0
0
12
% K
% Leu:
12
0
12
0
0
53
0
0
0
12
6
6
0
0
18
% L
% Met:
53
12
0
0
59
0
0
0
0
0
0
0
0
6
0
% M
% Asn:
6
0
0
0
0
0
0
0
6
0
6
12
6
0
36
% N
% Pro:
6
6
0
0
0
0
0
0
0
0
0
0
0
6
6
% P
% Gln:
0
0
0
12
6
6
0
0
6
0
6
12
0
0
0
% Q
% Arg:
0
6
0
6
0
6
6
0
6
12
0
0
0
0
6
% R
% Ser:
0
6
12
53
0
0
12
24
0
48
0
18
6
6
6
% S
% Thr:
6
0
0
0
6
0
0
53
0
12
6
0
0
0
0
% T
% Val:
0
6
0
12
0
6
0
0
6
0
6
0
6
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
36
0
6
0
0
0
53
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _