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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
11.52
Human Site:
Y199
Identified Species:
15.83
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
Y199
P
H
I
H
A
R
V
Y
N
Y
E
P
L
T
Q
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
Y199
P
H
I
H
A
R
V
Y
N
Y
E
P
L
T
Q
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
Y199
P
H
I
H
A
R
V
Y
N
Y
E
P
L
T
Q
Dog
Lupus familis
XP_534352
833
93150
L197
R
V
Y
N
Y
E
P
L
T
H
L
K
N
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
T198
V
Y
N
Y
E
P
L
T
H
L
K
N
I
R
A
Rat
Rattus norvegicus
NP_001099984
830
91958
K198
Y
E
P
L
T
H
L
K
N
I
R
A
T
C
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
F202
L
K
N
V
R
A
N
F
Y
G
K
F
V
A
L
Chicken
Gallus gallus
XP_001232579
830
92790
N200
E
P
L
T
Q
L
K
N
V
R
A
N
C
Y
G
Frog
Xenopus laevis
P55861
886
100243
V217
E
N
K
E
S
L
P
V
N
Y
E
D
L
A
A
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
Y206
V
T
L
P
D
G
K
Y
T
M
P
T
K
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
H267
E
R
V
T
T
E
I
H
V
R
I
S
E
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
I205
T
F
V
D
F
Q
K
I
R
I
Q
E
T
Q
A
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
L199
P
L
I
H
A
R
I
L
N
Y
E
P
T
T
A
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
M167
V
R
P
L
V
V
Q
M
N
F
N
C
A
K
C
Maize
Zea mays
Q43704
768
85163
K190
E
Y
G
M
C
E
Y
K
D
H
Q
T
L
S
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
N198
S
I
Q
E
V
P
E
N
A
A
P
G
Q
L
P
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
F268
R
V
F
Q
I
S
F
F
N
L
P
T
V
H
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
100
0
N.A.
0
6.6
N.A.
0
0
26.6
6.6
N.A.
0
N.A.
0
66.6
P-Site Similarity:
100
100
100
20
N.A.
40
13.3
N.A.
20
6.6
40
13.3
N.A.
20
N.A.
20
73.3
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
6.6
N.A.
P-Site Similarity:
13.3
40
N.A.
0
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
24
6
0
0
6
6
6
6
6
12
24
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
6
6
12
6
% C
% Asp:
0
0
0
6
6
0
0
0
6
0
0
6
0
0
0
% D
% Glu:
24
6
0
12
6
18
6
0
0
0
30
6
6
0
0
% E
% Phe:
0
6
6
0
6
0
6
12
0
6
0
6
0
0
0
% F
% Gly:
0
0
6
0
0
6
0
0
0
6
0
6
0
0
6
% G
% His:
0
18
0
24
0
6
0
6
6
12
0
0
0
6
0
% H
% Ile:
0
6
24
0
6
0
12
6
0
12
6
0
6
0
0
% I
% Lys:
0
6
6
0
0
0
18
12
0
0
12
6
6
6
0
% K
% Leu:
6
6
12
12
0
12
12
12
0
12
6
0
30
12
12
% L
% Met:
0
0
0
6
0
0
0
6
0
6
0
0
0
0
6
% M
% Asn:
0
6
12
6
0
0
6
12
48
0
6
12
6
0
0
% N
% Pro:
24
6
12
6
0
12
12
0
0
0
18
24
0
0
12
% P
% Gln:
0
0
6
6
6
6
6
0
0
0
12
0
6
6
18
% Q
% Arg:
12
12
0
0
6
24
0
0
6
12
6
0
0
6
12
% R
% Ser:
6
0
0
0
6
6
0
0
0
0
0
6
0
6
0
% S
% Thr:
6
6
0
12
12
0
0
6
12
0
0
18
18
24
0
% T
% Val:
18
12
12
6
12
6
18
6
12
0
0
0
12
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
12
6
6
6
0
6
24
6
30
0
0
0
6
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _