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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM8
All Species:
10.91
Human Site:
Y75
Identified Species:
15
UniProt:
Q9UJA3
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA3
NP_115874.3
840
93697
Y75
T
L
D
R
F
I
P
Y
K
G
W
K
L
Y
F
Chimpanzee
Pan troglodytes
XP_001166964
840
93670
Y75
T
L
D
R
F
I
P
Y
K
G
W
K
L
Y
F
Rhesus Macaque
Macaca mulatta
XP_001115843
840
93650
Y75
T
L
D
Q
L
I
P
Y
K
G
W
K
L
Y
F
Dog
Lupus familis
XP_534352
833
93150
F75
Y
K
G
W
K
L
Y
F
S
E
V
Y
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CWV1
833
92353
F75
Y
K
G
W
K
L
Y
F
S
E
V
Y
S
N
N
Rat
Rattus norvegicus
NP_001099984
830
91958
V75
W
K
L
Y
F
S
E
V
Y
S
N
N
S
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514432
828
92086
F80
V
Y
S
D
C
S
P
F
V
E
K
T
Q
A
F
Chicken
Gallus gallus
XP_001232579
830
92790
Y77
K
L
Y
F
S
E
A
Y
A
D
K
S
P
F
V
Frog
Xenopus laevis
P55861
886
100243
E78
E
L
D
R
Y
E
V
E
G
L
D
D
E
E
D
Zebra Danio
Brachydanio rerio
XP_002665161
788
87122
L76
I
L
V
D
Y
K
D
L
L
S
N
K
Q
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49735
887
100396
L82
D
H
Y
D
P
A
L
L
D
D
E
D
D
F
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34647
810
91112
L75
N
L
A
T
T
I
E
L
Q
Y
Y
R
V
Y
P
Sea Urchin
Strong. purpuratus
XP_797782
848
93611
D76
T
D
E
T
Y
S
S
D
S
P
T
V
T
K
I
Poplar Tree
Populus trichocarpa
XP_002326332
745
82557
L45
V
D
E
E
K
L
M
L
T
C
H
L
I
H
F
Maize
Zea mays
Q43704
768
85163
Y68
V
I
R
T
P
G
E
Y
M
Q
P
A
S
D
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FL33
776
86338
T75
C
D
A
A
T
E
A
T
R
A
I
D
P
K
Y
Baker's Yeast
Sacchar. cerevisiae
P53091
1017
112934
F92
G
N
E
P
A
R
S
F
K
S
R
A
L
N
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97
92.2
N.A.
89.2
89.7
N.A.
82.9
77.8
28.6
68.9
N.A.
25.8
N.A.
24.2
64.5
Protein Similarity:
100
99.8
98
95.8
N.A.
94.4
94
N.A.
90.5
87.2
47.2
80.8
N.A.
44.7
N.A.
43.6
77.1
P-Site Identity:
100
100
86.6
0
N.A.
0
6.6
N.A.
13.3
13.3
20
13.3
N.A.
0
N.A.
20
6.6
P-Site Similarity:
100
100
93.3
13.3
N.A.
13.3
6.6
N.A.
20
20
26.6
20
N.A.
6.6
N.A.
46.6
20
Percent
Protein Identity:
43.4
27.1
N.A.
27.7
25
N.A.
Protein Similarity:
61.3
48.6
N.A.
48.6
42.9
N.A.
P-Site Identity:
6.6
6.6
N.A.
0
13.3
N.A.
P-Site Similarity:
33.3
13.3
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
6
6
6
12
0
6
6
0
12
0
6
6
% A
% Cys:
6
0
0
0
6
0
0
0
0
6
0
0
0
0
0
% C
% Asp:
6
18
24
18
0
0
6
6
6
12
6
18
6
6
6
% D
% Glu:
6
0
18
6
0
18
18
6
0
18
6
0
6
6
0
% E
% Phe:
0
0
0
6
18
0
0
24
0
0
0
0
0
12
30
% F
% Gly:
6
0
12
0
0
6
0
0
6
18
0
0
0
0
0
% G
% His:
0
6
0
0
0
0
0
0
0
0
6
0
0
6
6
% H
% Ile:
6
6
0
0
0
24
0
0
0
0
6
0
6
0
6
% I
% Lys:
6
18
0
0
18
6
0
0
24
0
12
24
0
12
0
% K
% Leu:
0
42
6
0
6
18
6
24
6
6
0
6
24
0
6
% L
% Met:
0
0
0
0
0
0
6
0
6
0
0
0
0
0
0
% M
% Asn:
6
6
0
0
0
0
0
0
0
0
12
6
0
12
6
% N
% Pro:
0
0
0
6
12
0
24
0
0
6
6
0
12
6
6
% P
% Gln:
0
0
0
6
0
0
0
0
6
6
0
0
12
0
0
% Q
% Arg:
0
0
6
18
0
6
0
0
6
0
6
6
0
0
0
% R
% Ser:
0
0
6
0
6
18
12
0
18
18
0
6
24
6
18
% S
% Thr:
24
0
0
18
12
0
0
6
6
0
6
6
6
0
0
% T
% Val:
18
0
6
0
0
0
6
6
6
0
12
6
6
6
6
% V
% Trp:
6
0
0
12
0
0
0
0
0
0
18
0
0
0
0
% W
% Tyr:
12
6
12
6
18
0
12
30
6
6
6
12
0
24
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _