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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM8 All Species: 40.3
Human Site: Y826 Identified Species: 55.42
UniProt: Q9UJA3 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.19
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJA3 NP_115874.3 840 93697 Y826 G S L N D Q G Y L L K K G P K
Chimpanzee Pan troglodytes XP_001166964 840 93670 Y826 G S L N D Q G Y L L K K G P K
Rhesus Macaque Macaca mulatta XP_001115843 840 93650 Y826 G S L N D Q G Y L L K K G P K
Dog Lupus familis XP_534352 833 93150 Y819 G S L N D Q G Y L L K K G P K
Cat Felis silvestris
Mouse Mus musculus Q9CWV1 833 92353 Y819 G S L N D Q G Y L L K K G P K
Rat Rattus norvegicus NP_001099984 830 91958 Y816 G S L N D Q G Y L L K K G P K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514432 828 92086 Y814 G S L N D Q G Y L L K K G P K
Chicken Gallus gallus XP_001232579 830 92790 Y816 E S L N D Q G Y L L K K G S R
Frog Xenopus laevis P55861 886 100243 F868 A F Y D S D L F K M N K F T H
Zebra Danio Brachydanio rerio XP_002665161 788 87122 Y774 C A L N E Q G Y L L K K G H R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P49735 887 100396 Y870 F R T N G F S Y D P K R R I I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34647 810 91112 E795 L L E V E Q G E D P T L C V H
Sea Urchin Strong. purpuratus XP_797782 848 93611 Y832 A S L N N Q N Y L L K K G P R
Poplar Tree Populus trichocarpa XP_002326332 745 82557 V732 K G P K T F Q V L T S S Y S R
Maize Zea mays Q43704 768 85163 A755 I L E R M Q D A N R V M I R D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FL33 776 86338 D763 L L E K L Q D D N K V M I S D
Baker's Yeast Sacchar. cerevisiae P53091 1017 112934 E956 G S L A E Y W E E R R L A F K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 97 92.2 N.A. 89.2 89.7 N.A. 82.9 77.8 28.6 68.9 N.A. 25.8 N.A. 24.2 64.5
Protein Similarity: 100 99.8 98 95.8 N.A. 94.4 94 N.A. 90.5 87.2 47.2 80.8 N.A. 44.7 N.A. 43.6 77.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 100 80 6.6 66.6 N.A. 20 N.A. 13.3 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 86.6 26.6 86.6 N.A. 26.6 N.A. 20 86.6
Percent
Protein Identity: 43.4 27.1 N.A. 27.7 25 N.A.
Protein Similarity: 61.3 48.6 N.A. 48.6 42.9 N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 26.6 N.A.
P-Site Similarity: 13.3 6.6 N.A. 6.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 6 0 6 0 0 0 6 0 0 0 0 6 0 0 % A
% Cys: 6 0 0 0 0 0 0 0 0 0 0 0 6 0 0 % C
% Asp: 0 0 0 6 48 6 12 6 12 0 0 0 0 0 12 % D
% Glu: 6 0 18 0 18 0 0 12 6 0 0 0 0 0 0 % E
% Phe: 6 6 0 0 0 12 0 6 0 0 0 0 6 6 0 % F
% Gly: 48 6 0 0 6 0 59 0 0 0 0 0 59 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 12 % H
% Ile: 6 0 0 0 0 0 0 0 0 0 0 0 12 6 6 % I
% Lys: 6 0 0 12 0 0 0 0 6 6 65 65 0 0 48 % K
% Leu: 12 18 65 0 6 0 6 0 65 59 0 12 0 0 0 % L
% Met: 0 0 0 0 6 0 0 0 0 6 0 12 0 0 0 % M
% Asn: 0 0 0 65 6 0 6 0 12 0 6 0 0 0 0 % N
% Pro: 0 0 6 0 0 0 0 0 0 12 0 0 0 48 0 % P
% Gln: 0 0 0 0 0 77 6 0 0 0 0 0 0 0 0 % Q
% Arg: 0 6 0 6 0 0 0 0 0 12 6 6 6 6 24 % R
% Ser: 0 59 0 0 6 0 6 0 0 0 6 6 0 18 0 % S
% Thr: 0 0 6 0 6 0 0 0 0 6 6 0 0 6 0 % T
% Val: 0 0 0 6 0 0 0 6 0 0 12 0 0 6 0 % V
% Trp: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 6 0 65 0 0 0 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _