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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENPP5
All Species:
8.79
Human Site:
Y309
Identified Species:
19.33
UniProt:
Q9UJA9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJA9
NP_067547.1
477
54666
Y309
P
E
R
W
H
Y
K
Y
N
S
R
I
Q
P
I
Chimpanzee
Pan troglodytes
XP_001143218
474
54368
H306
P
E
R
W
H
Y
K
H
N
S
R
I
Q
P
I
Rhesus Macaque
Macaca mulatta
XP_001094592
496
56717
Y309
P
E
R
W
H
Y
K
Y
N
N
R
I
Q
P
I
Dog
Lupus familis
XP_538945
477
54680
Y309
P
E
R
W
H
Y
K
Y
N
H
R
I
Q
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQG7
477
54368
H309
P
E
R
W
H
Y
K
H
N
D
R
V
Q
P
I
Rat
Rattus norvegicus
P84039
477
54271
H309
P
E
R
W
H
Y
K
H
S
D
R
V
Q
P
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511525
784
89004
H619
P
E
R
L
H
Y
K
H
N
H
K
I
Q
P
I
Chicken
Gallus gallus
NP_001006422
331
38022
G190
W
E
E
P
D
A
S
G
H
K
Y
G
P
D
D
Frog
Xenopus laevis
Q6AX80
452
51293
H307
P
D
R
W
H
Y
K
H
N
S
R
I
Q
P
L
Zebra Danio
Brachydanio rerio
Q566N0
459
51584
N311
P
D
R
L
H
Y
K
N
N
E
R
I
Q
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25353
742
84715
F493
N
F
P
K
E
W
N
F
N
D
G
K
N
H
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
89.9
87.6
N.A.
81.7
81.7
N.A.
46.6
36.4
44.8
42.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
93.5
92.6
N.A.
90.5
91.6
N.A.
53.5
49
63.5
58.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
93.3
N.A.
80
73.3
N.A.
73.3
6.6
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
13.3
100
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
10
0
0
0
0
28
0
0
0
10
10
% D
% Glu:
0
73
10
0
10
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
10
10
0
0
0
% G
% His:
0
0
0
0
82
0
0
46
10
19
0
0
0
10
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
64
0
0
73
% I
% Lys:
0
0
0
10
0
0
82
0
0
10
10
10
0
0
0
% K
% Leu:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
10
10
82
10
0
0
10
0
0
% N
% Pro:
82
0
10
10
0
0
0
0
0
0
0
0
10
82
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
82
0
0
% Q
% Arg:
0
0
82
0
0
0
0
0
0
0
73
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
0
10
28
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% V
% Trp:
10
0
0
64
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
82
0
28
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _