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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOOK1
All Species:
19.7
Human Site:
S167
Identified Species:
33.33
UniProt:
Q9UJC3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJC3
NP_056972.1
728
84648
S167
M
S
K
E
I
L
S
S
P
P
N
D
A
V
G
Chimpanzee
Pan troglodytes
XP_513444
728
84599
S167
M
S
K
E
I
L
S
S
P
P
N
D
A
V
G
Rhesus Macaque
Macaca mulatta
XP_001082586
728
84703
F167
M
S
K
E
I
L
S
F
P
L
N
D
A
V
G
Dog
Lupus familis
XP_536692
791
91437
S230
M
S
K
E
I
L
N
S
P
T
N
D
T
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIL5
728
84420
S167
M
S
K
E
I
V
I
S
P
A
S
D
T
V
G
Rat
Rattus norvegicus
NP_001101416
728
84353
S167
M
S
K
E
I
V
S
S
P
A
S
D
A
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517614
756
85046
P241
M
R
K
E
T
P
G
P
A
A
P
A
H
G
A
Chicken
Gallus gallus
Q5ZJ27
718
82961
P163
M
S
K
E
A
M
G
P
S
A
S
D
V
S
S
Frog
Xenopus laevis
Q6GQ73
719
83201
S162
M
S
K
E
T
P
V
S
I
G
T
D
A
Y
A
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
Q161
M
S
R
E
S
V
S
Q
L
G
A
E
P
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24185
679
76646
T162
E
A
T
R
Q
A
S
T
P
E
G
G
V
A
S
Honey Bee
Apis mellifera
XP_395724
701
81483
R158
E
S
N
M
H
G
P
R
L
S
L
G
T
S
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796541
586
67269
F140
K
L
D
H
G
D
T
F
G
D
P
S
T
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
Q185
S
L
M
K
P
K
A
Q
G
P
H
D
E
G
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
88.1
N.A.
92.5
92.7
N.A.
65.7
78.3
56.8
64.1
N.A.
33.7
38.5
N.A.
39.8
Protein Similarity:
100
99.8
99.1
90
N.A.
96
96.2
N.A.
75.9
89.5
74.1
82.4
N.A.
54.6
61.8
N.A.
56
P-Site Identity:
100
100
86.6
80
N.A.
66.6
80
N.A.
20
33.3
46.6
33.3
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
86.6
86.6
N.A.
80
93.3
N.A.
20
46.6
46.6
53.3
N.A.
26.6
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
8
0
8
29
8
8
36
15
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
8
0
65
0
0
0
% D
% Glu:
15
0
0
72
0
0
0
0
0
8
0
8
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
8
8
15
0
15
15
8
15
0
15
50
% G
% His:
0
0
0
8
8
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
0
0
0
0
43
0
8
0
8
0
0
0
0
0
0
% I
% Lys:
8
0
65
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
0
0
0
29
0
0
15
8
8
0
0
0
8
% L
% Met:
72
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
0
29
0
0
0
0
% N
% Pro:
0
0
0
0
8
15
8
15
50
22
15
0
8
8
0
% P
% Gln:
0
0
0
0
8
0
0
15
0
0
0
0
0
0
0
% Q
% Arg:
0
8
8
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
72
0
0
8
0
43
43
8
8
22
8
0
15
15
% S
% Thr:
0
0
8
0
15
0
8
8
0
8
8
0
29
0
0
% T
% Val:
0
0
0
0
0
22
8
0
0
0
0
0
15
43
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _