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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOOK1
All Species:
39.09
Human Site:
S217
Identified Species:
66.15
UniProt:
Q9UJC3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJC3
NP_056972.1
728
84648
S217
T
L
Q
D
E
K
N
S
L
V
S
E
N
E
M
Chimpanzee
Pan troglodytes
XP_513444
728
84599
S217
T
L
Q
D
E
K
N
S
L
V
S
E
N
E
M
Rhesus Macaque
Macaca mulatta
XP_001082586
728
84703
S217
T
L
Q
D
E
K
N
S
L
V
S
E
N
E
M
Dog
Lupus familis
XP_536692
791
91437
S280
A
L
Q
D
E
K
N
S
L
V
S
E
N
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIL5
728
84420
S217
T
L
Q
D
E
K
N
S
L
V
S
E
N
E
M
Rat
Rattus norvegicus
NP_001101416
728
84353
S217
A
L
Q
D
E
K
N
S
L
V
S
E
N
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517614
756
85046
T292
A
L
Q
D
E
K
N
T
L
L
S
E
N
E
L
Chicken
Gallus gallus
Q5ZJ27
718
82961
S213
A
L
Q
D
E
K
N
S
L
V
S
E
N
E
I
Frog
Xenopus laevis
Q6GQ73
719
83201
S212
G
L
Q
E
E
K
S
S
L
L
A
E
N
Q
I
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
S211
V
L
Q
E
E
R
N
S
L
L
A
E
N
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24185
679
76646
N212
L
L
I
D
E
K
T
N
L
Q
Q
E
L
H
K
Honey Bee
Apis mellifera
XP_395724
701
81483
A214
L
L
Q
E
E
K
A
A
L
M
T
E
N
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796541
586
67269
A163
N
E
Q
L
Q
N
L
A
E
E
A
R
S
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
G225
T
L
N
E
S
R
S
G
V
V
Q
M
V
K
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
88.1
N.A.
92.5
92.7
N.A.
65.7
78.3
56.8
64.1
N.A.
33.7
38.5
N.A.
39.8
Protein Similarity:
100
99.8
99.1
90
N.A.
96
96.2
N.A.
75.9
89.5
74.1
82.4
N.A.
54.6
61.8
N.A.
56
P-Site Identity:
100
100
100
93.3
N.A.
100
93.3
N.A.
73.3
86.6
53.3
53.3
N.A.
40
46.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
93.3
N.A.
93.3
93.3
93.3
93.3
N.A.
46.6
80
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
0
0
0
0
0
8
15
0
0
22
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
65
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
8
0
29
86
0
0
0
8
8
0
86
0
58
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
0
0
0
0
0
79
0
0
0
0
0
0
0
15
22
% K
% Leu:
15
93
0
8
0
0
8
0
86
22
0
0
8
8
22
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
43
% M
% Asn:
8
0
8
0
0
8
65
8
0
0
0
0
79
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
86
0
8
0
0
0
0
8
15
0
0
8
0
% Q
% Arg:
0
0
0
0
0
15
0
0
0
0
0
8
0
0
0
% R
% Ser:
0
0
0
0
8
0
15
65
0
0
58
0
8
0
0
% S
% Thr:
36
0
0
0
0
0
8
8
0
0
8
0
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
8
58
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _