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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOOK1
All Species:
22.73
Human Site:
S542
Identified Species:
38.46
UniProt:
Q9UJC3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJC3
NP_056972.1
728
84648
S542
G
S
K
S
E
G
E
S
S
S
K
L
K
Q
K
Chimpanzee
Pan troglodytes
XP_513444
728
84599
S542
G
S
K
S
E
G
E
S
S
S
K
L
K
Q
K
Rhesus Macaque
Macaca mulatta
XP_001082586
728
84703
S542
G
S
K
S
E
G
E
S
S
S
K
L
K
Q
K
Dog
Lupus familis
XP_536692
791
91437
S605
G
S
K
S
E
G
E
S
S
S
K
L
K
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIL5
728
84420
S542
G
S
K
S
E
G
E
S
S
S
K
L
K
Q
K
Rat
Rattus norvegicus
NP_001101416
728
84353
S542
G
S
K
S
E
G
E
S
S
S
K
L
K
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517614
756
85046
A609
L
Q
D
Q
G
A
K
A
E
N
E
G
S
S
K
Chicken
Gallus gallus
Q5ZJ27
718
82961
G536
E
Q
G
S
K
T
E
G
S
S
N
L
K
Q
K
Frog
Xenopus laevis
Q6GQ73
719
83201
D537
E
Q
G
A
K
T
E
D
S
L
L
L
K
K
K
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
H537
G
A
K
P
D
D
S
H
L
K
R
K
L
D
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24185
679
76646
I531
E
S
E
F
G
K
Q
I
K
Q
L
M
E
L
N
Honey Bee
Apis mellifera
XP_395724
701
81483
N530
D
N
K
T
D
N
I
N
L
G
Q
K
I
T
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796541
586
67269
P441
A
H
I
D
D
L
E
P
K
F
T
N
T
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
D983
G
Y
K
K
K
L
N
D
L
Q
I
A
F
T
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
88.1
N.A.
92.5
92.7
N.A.
65.7
78.3
56.8
64.1
N.A.
33.7
38.5
N.A.
39.8
Protein Similarity:
100
99.8
99.1
90
N.A.
96
96.2
N.A.
75.9
89.5
74.1
82.4
N.A.
54.6
61.8
N.A.
56
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
53.3
33.3
13.3
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
33.3
60
53.3
33.3
N.A.
33.3
46.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
0
8
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
22
8
0
15
0
0
0
0
0
8
0
% D
% Glu:
22
0
8
0
43
0
65
0
8
0
8
0
8
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
58
0
15
0
15
43
0
8
0
8
0
8
0
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
8
8
0
0
8
0
8
0
0
% I
% Lys:
0
0
65
8
22
8
8
0
15
8
43
15
58
8
72
% K
% Leu:
8
0
0
0
0
15
0
0
22
8
15
58
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
0
8
8
8
0
8
8
8
0
8
8
% N
% Pro:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
22
0
8
0
0
8
0
0
15
8
0
0
50
8
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
50
0
50
0
0
8
43
58
50
0
0
8
8
0
% S
% Thr:
0
0
0
8
0
15
0
0
0
0
8
0
8
15
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _