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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOOK1
All Species:
21.52
Human Site:
S687
Identified Species:
36.41
UniProt:
Q9UJC3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJC3
NP_056972.1
728
84648
S687
G
M
E
S
R
L
V
S
G
G
G
A
C
S
D
Chimpanzee
Pan troglodytes
XP_513444
728
84599
S687
G
M
E
S
R
L
V
S
G
G
G
A
C
S
D
Rhesus Macaque
Macaca mulatta
XP_001082586
728
84703
S687
G
M
E
S
R
L
V
S
G
G
G
A
C
N
D
Dog
Lupus familis
XP_536692
791
91437
S750
G
M
E
S
R
L
V
S
G
S
G
A
C
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIL5
728
84420
S687
G
M
E
S
R
L
V
S
G
A
S
A
C
K
D
Rat
Rattus norvegicus
NP_001101416
728
84353
S687
G
M
E
S
R
L
V
S
G
A
S
A
C
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517614
756
85046
G714
G
M
E
S
R
L
I
G
H
G
A
G
P
G
K
Chicken
Gallus gallus
Q5ZJ27
718
82961
A677
L
Q
K
L
G
M
E
A
R
L
L
G
S
G
G
Frog
Xenopus laevis
Q6GQ73
719
83201
K675
N
M
G
M
T
L
H
K
K
A
A
E
D
R
L
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
E674
N
F
Q
K
M
A
I
E
S
R
L
S
G
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24185
679
76646
L637
M
T
S
A
F
Y
R
L
G
V
N
A
Q
R
D
Honey Bee
Apis mellifera
XP_395724
701
81483
S637
I
M
E
D
M
E
R
S
L
K
E
S
K
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796541
586
67269
R546
N
L
G
M
Q
L
H
R
K
A
A
E
D
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
G1108
Y
Q
M
I
T
L
G
G
D
A
E
L
E
L
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
88.1
N.A.
92.5
92.7
N.A.
65.7
78.3
56.8
64.1
N.A.
33.7
38.5
N.A.
39.8
Protein Similarity:
100
99.8
99.1
90
N.A.
96
96.2
N.A.
75.9
89.5
74.1
82.4
N.A.
54.6
61.8
N.A.
56
P-Site Identity:
100
100
93.3
86.6
N.A.
80
80
N.A.
46.6
0
13.3
0
N.A.
20
20
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
80
N.A.
53.3
20
13.3
20
N.A.
26.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
8
0
36
22
50
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
43
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
8
0
0
0
15
0
50
% D
% Glu:
0
0
58
0
0
8
8
8
0
0
15
15
8
0
0
% E
% Phe:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
15
0
8
0
8
15
50
29
29
15
8
15
8
% G
% His:
0
0
0
0
0
0
15
0
8
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
15
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
8
8
0
0
0
8
15
8
0
0
8
22
8
% K
% Leu:
8
8
0
8
0
72
0
8
8
8
15
8
0
15
15
% L
% Met:
8
65
8
15
15
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
22
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
15
8
0
8
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
0
50
0
15
8
8
8
0
0
0
29
0
% R
% Ser:
0
0
8
50
0
0
0
50
8
8
15
15
8
15
0
% S
% Thr:
0
8
0
0
15
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
43
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _