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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HOOK1 All Species: 39.09
Human Site: T373 Identified Species: 66.15
UniProt: Q9UJC3 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJC3 NP_056972.1 728 84648 T373 A A R T Q L E T Y K R Q V Q D
Chimpanzee Pan troglodytes XP_513444 728 84599 T373 A A R T Q L E T Y K R Q V Q D
Rhesus Macaque Macaca mulatta XP_001082586 728 84703 T373 A A R T Q L E T Y K R Q V Q D
Dog Lupus familis XP_536692 791 91437 T436 A A R T Q L E T Y K R Q V Q D
Cat Felis silvestris
Mouse Mus musculus Q8BIL5 728 84420 T373 A A R A Q L E T Y K R Q V Q D
Rat Rattus norvegicus NP_001101416 728 84353 T373 A A R A Q L E T Y K R Q V Q D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517614 756 85046 T448 A A R A Q L E T H K R Q I Q E
Chicken Gallus gallus Q5ZJ27 718 82961 T369 A A R A Q L E T Y K R Q V Q E
Frog Xenopus laevis Q6GQ73 719 83201 T367 A A R S Q L E T Y K R Q V V E
Zebra Danio Brachydanio rerio Q5TZ80 715 83097 T366 A A R A Q L E T Y K R Q V Q E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24185 679 76646 L377 N T K G Q V E L F K K E I Q D
Honey Bee Apis mellifera XP_395724 701 81483 V366 M L R N H L E V C K Q Q L A E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796541 586 67269 L302 E E L T L N Q L Q G N A F G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJL0 1241 141112 N817 K E E K E I E N L E K G S K Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.6 88.1 N.A. 92.5 92.7 N.A. 65.7 78.3 56.8 64.1 N.A. 33.7 38.5 N.A. 39.8
Protein Similarity: 100 99.8 99.1 90 N.A. 96 96.2 N.A. 75.9 89.5 74.1 82.4 N.A. 54.6 61.8 N.A. 56
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 73.3 86.6 80 86.6 N.A. 33.3 33.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 93.3 93.3 93.3 N.A. 73.3 53.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. 21.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 72 72 0 36 0 0 0 0 0 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % D
% Glu: 8 15 8 0 8 0 93 0 0 8 0 8 0 0 43 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 8 0 8 0 8 0 % G
% His: 0 0 0 0 8 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 15 0 0 % I
% Lys: 8 0 8 8 0 0 0 0 0 86 15 0 0 8 0 % K
% Leu: 0 8 8 0 8 79 0 15 8 0 0 0 8 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 8 0 8 0 8 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 79 0 8 0 8 0 8 79 0 72 8 % Q
% Arg: 0 0 79 0 0 0 0 0 0 0 72 0 0 0 0 % R
% Ser: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % S
% Thr: 0 8 0 36 0 0 0 72 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 8 0 0 0 0 65 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 65 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _