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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOOK1
All Species:
30.61
Human Site:
T422
Identified Species:
51.79
UniProt:
Q9UJC3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJC3
NP_056972.1
728
84648
T422
R
L
I
E
Q
R
D
T
L
K
E
T
N
E
E
Chimpanzee
Pan troglodytes
XP_513444
728
84599
T422
R
L
I
E
Q
R
D
T
L
K
E
T
N
E
E
Rhesus Macaque
Macaca mulatta
XP_001082586
728
84703
T422
R
L
I
E
Q
R
D
T
L
K
E
T
N
E
E
Dog
Lupus familis
XP_536692
791
91437
T485
R
L
I
E
Q
R
D
T
L
K
E
T
N
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIL5
728
84420
T422
R
L
I
E
Q
R
D
T
L
K
E
T
N
E
E
Rat
Rattus norvegicus
NP_001101416
728
84353
T422
R
L
I
E
Q
R
D
T
L
K
E
T
N
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517614
756
85046
T497
R
L
I
I
Q
R
D
T
L
K
E
T
N
E
E
Chicken
Gallus gallus
Q5ZJ27
718
82961
A418
R
L
V
I
Q
C
D
A
L
K
E
T
N
E
E
Frog
Xenopus laevis
Q6GQ73
719
83201
S416
R
L
R
S
E
R
D
S
L
K
E
T
I
E
E
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
R417
S
I
E
R
D
T
L
R
E
T
N
E
E
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24185
679
76646
N426
S
L
L
K
E
R
D
N
L
R
E
A
V
D
E
Honey Bee
Apis mellifera
XP_395724
701
81483
A415
R
L
I
V
E
R
D
A
L
K
E
T
N
E
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796541
586
67269
Q338
R
E
K
M
I
R
L
Q
H
E
N
K
M
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
D854
K
V
E
K
I
Q
T
D
I
D
K
N
N
T
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
88.1
N.A.
92.5
92.7
N.A.
65.7
78.3
56.8
64.1
N.A.
33.7
38.5
N.A.
39.8
Protein Similarity:
100
99.8
99.1
90
N.A.
96
96.2
N.A.
75.9
89.5
74.1
82.4
N.A.
54.6
61.8
N.A.
56
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
73.3
66.6
0
N.A.
40
80
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
80
80
6.6
N.A.
73.3
86.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
15
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
79
8
0
8
0
0
0
8
0
% D
% Glu:
0
8
15
43
22
0
0
0
8
8
79
8
8
72
86
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
58
15
15
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
8
0
8
15
0
0
0
0
0
72
8
8
0
0
8
% K
% Leu:
0
79
8
0
0
0
15
0
79
0
0
0
0
15
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
15
8
72
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
58
8
0
8
0
0
0
0
0
0
0
% Q
% Arg:
79
0
8
8
0
79
0
8
0
8
0
0
0
0
8
% R
% Ser:
15
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
8
50
0
8
0
72
0
8
0
% T
% Val:
0
8
8
8
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _