Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HOOK1 All Species: 31.21
Human Site: Y247 Identified Species: 52.82
UniProt: Q9UJC3 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJC3 NP_056972.1 728 84648 Y247 N T V V A K K Y F H A Q L Q L
Chimpanzee Pan troglodytes XP_513444 728 84599 Y247 N T V V A K K Y F H A Q L Q L
Rhesus Macaque Macaca mulatta XP_001082586 728 84703 Y247 N T V V A K K Y F H A Q L Q L
Dog Lupus familis XP_536692 791 91437 Y310 N T M V A K K Y F H A Q L Q L
Cat Felis silvestris
Mouse Mus musculus Q8BIL5 728 84420 Y247 N T M V A K K Y F H V Q L Q L
Rat Rattus norvegicus NP_001101416 728 84353 Y247 N T M V A K K Y F H V Q L Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517614 756 85046 Y322 G T V V A K K Y F H A Q L Q V
Chicken Gallus gallus Q5ZJ27 718 82961 Y243 N T V V A K K Y F H A Q L Q L
Frog Xenopus laevis Q6GQ73 719 83201 L242 S P A G R R H L Q L Q T Q L E
Zebra Danio Brachydanio rerio Q5TZ80 715 83097 S241 T P S G R K H S Q L Q F Q L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24185 679 76646 G242 G D D G V S L G P V Q T G S V
Honey Bee Apis mellifera XP_395724 701 81483 R244 I F R H S G L R K Q V E A L K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796541 586 67269 L193 Y E G T I D T L K K K L E D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FJL0 1241 141112 L255 E T Y M L K E L S H L K W Q E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.6 88.1 N.A. 92.5 92.7 N.A. 65.7 78.3 56.8 64.1 N.A. 33.7 38.5 N.A. 39.8
Protein Similarity: 100 99.8 99.1 90 N.A. 96 96.2 N.A. 75.9 89.5 74.1 82.4 N.A. 54.6 61.8 N.A. 56
P-Site Identity: 100 100 100 93.3 N.A. 86.6 86.6 N.A. 86.6 100 0 6.6 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 100 13.3 6.6 N.A. 6.6 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. 21.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 58 0 0 0 0 0 43 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 0 0 8 0 0 0 0 0 0 0 8 0 % D
% Glu: 8 8 0 0 0 0 8 0 0 0 0 8 8 0 22 % E
% Phe: 0 8 0 0 0 0 0 0 58 0 0 8 0 0 0 % F
% Gly: 15 0 8 22 0 8 0 8 0 0 0 0 8 0 0 % G
% His: 0 0 0 8 0 0 15 0 0 65 0 0 0 0 0 % H
% Ile: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 72 58 0 15 8 8 8 0 0 8 % K
% Leu: 0 0 0 0 8 0 15 22 0 15 8 8 58 22 58 % L
% Met: 0 0 22 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 15 0 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 15 8 22 58 15 65 0 % Q
% Arg: 0 0 8 0 15 8 0 8 0 0 0 0 0 0 0 % R
% Ser: 8 0 8 0 8 8 0 8 8 0 0 0 0 8 0 % S
% Thr: 8 65 0 8 0 0 8 0 0 0 0 15 0 0 0 % T
% Val: 0 0 36 58 8 0 0 0 0 8 22 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 8 0 8 0 0 0 0 58 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _