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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HOOK1
All Species:
27.88
Human Site:
Y660
Identified Species:
47.18
UniProt:
Q9UJC3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJC3
NP_056972.1
728
84648
Y660
K
V
A
K
F
R
D
Y
E
E
K
L
I
V
S
Chimpanzee
Pan troglodytes
XP_513444
728
84599
Y660
K
V
A
K
F
R
D
Y
E
E
K
L
I
V
S
Rhesus Macaque
Macaca mulatta
XP_001082586
728
84703
Y660
K
V
A
K
F
R
D
Y
E
E
K
L
I
V
S
Dog
Lupus familis
XP_536692
791
91437
Y723
K
V
A
K
F
R
D
Y
E
E
K
L
I
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIL5
728
84420
Y660
K
V
A
K
L
R
D
Y
E
E
K
L
I
V
S
Rat
Rattus norvegicus
NP_001101416
728
84353
Y660
K
V
A
K
F
R
D
Y
E
E
K
L
I
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517614
756
85046
Y687
K
V
A
K
F
R
D
Y
E
E
K
L
I
V
S
Chicken
Gallus gallus
Q5ZJ27
718
82961
K650
E
A
E
Y
K
L
A
K
L
R
D
Y
E
E
N
Frog
Xenopus laevis
Q6GQ73
719
83201
F648
F
V
S
L
E
K
E
F
E
K
T
K
T
Q
R
Zebra Danio
Brachydanio rerio
Q5TZ80
715
83097
A647
L
E
R
E
C
E
Q
A
K
L
R
E
Y
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24185
679
76646
S610
D
A
S
V
L
E
K
S
A
D
L
V
E
E
E
Honey Bee
Apis mellifera
XP_395724
701
81483
N610
K
S
L
D
P
K
Q
N
N
S
S
P
N
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796541
586
67269
R519
I
E
H
L
E
H
E
R
D
K
S
K
I
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJL0
1241
141112
R1081
Q
Y
D
E
L
R
K
R
R
L
D
E
F
M
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
98.6
88.1
N.A.
92.5
92.7
N.A.
65.7
78.3
56.8
64.1
N.A.
33.7
38.5
N.A.
39.8
Protein Similarity:
100
99.8
99.1
90
N.A.
96
96.2
N.A.
75.9
89.5
74.1
82.4
N.A.
54.6
61.8
N.A.
56
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
100
0
13.3
0
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
100
13.3
46.6
20
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
50
0
0
0
8
8
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
50
0
8
8
15
0
0
0
0
% D
% Glu:
8
15
8
15
15
15
15
0
58
50
0
15
15
29
15
% E
% Phe:
8
0
0
0
43
0
0
8
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
58
0
0
% I
% Lys:
58
0
0
50
8
15
15
8
8
15
50
15
0
0
0
% K
% Leu:
8
0
8
15
22
8
0
0
8
15
8
50
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
8
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
8
0
0
0
0
0
15
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
8
0
0
58
0
15
8
8
8
0
0
0
15
% R
% Ser:
0
8
15
0
0
0
0
8
0
8
15
0
0
0
50
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
8
8
0
% T
% Val:
0
58
0
8
0
0
0
0
0
0
0
8
0
50
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
0
50
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _