KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METRN
All Species:
13.33
Human Site:
T219
Identified Species:
41.9
UniProt:
Q9UJH8
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJH8
NP_076947.1
293
31207
T219
A
A
R
V
L
R
Q
T
P
P
L
F
Q
A
G
Chimpanzee
Pan troglodytes
XP_001156928
293
31235
T219
A
A
R
V
L
R
Q
T
P
P
L
F
Q
A
G
Rhesus Macaque
Macaca mulatta
XP_001107238
124
13639
L64
R
G
S
G
E
E
G
L
T
S
I
R
T
P
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8C1Q4
291
31451
T217
V
A
R
V
I
R
Q
T
L
P
L
F
K
E
G
Rat
Rattus norvegicus
Q5Q0T9
291
31334
T217
A
T
R
V
I
R
Q
T
L
P
L
F
Q
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512630
240
26540
K169
A
A
L
I
H
R
Q
K
L
P
L
F
Q
P
A
Chicken
Gallus gallus
Frog
Xenopus laevis
A1L2K1
286
32125
K213
V
D
K
L
Y
R
Q
K
S
K
I
F
L
P
K
Zebra Danio
Brachydanio rerio
Q7ZV46
286
31691
T212
S
H
L
Y
R
Q
K
T
Q
V
F
V
S
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
37.2
N.A.
N.A.
80.5
80.5
N.A.
51.1
N.A.
41.6
40.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.9
38.5
N.A.
N.A.
84.3
84.9
N.A.
58.7
N.A.
58.7
57.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
66.6
73.3
N.A.
53.3
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
N.A.
N.A.
80
80
N.A.
60
N.A.
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
50
0
0
0
0
0
0
0
0
0
0
0
25
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
13
13
0
0
0
0
0
0
0
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
13
75
0
0
0
% F
% Gly:
0
13
0
13
0
0
13
0
0
0
0
0
0
13
63
% G
% His:
0
13
0
0
13
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
13
25
0
0
0
0
0
25
0
0
0
0
% I
% Lys:
0
0
13
0
0
0
13
25
0
13
0
0
13
0
13
% K
% Leu:
0
0
25
13
25
0
0
13
38
0
63
0
13
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
25
63
0
0
0
38
0
% P
% Gln:
0
0
0
0
0
13
75
0
13
0
0
0
50
0
0
% Q
% Arg:
13
0
50
0
13
75
0
0
0
0
0
13
0
0
0
% R
% Ser:
13
0
13
0
0
0
0
0
13
13
0
0
13
0
0
% S
% Thr:
0
13
0
0
0
0
0
63
13
0
0
0
13
0
0
% T
% Val:
25
0
0
50
0
0
0
0
0
13
0
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
13
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _