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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAO1 All Species: 42.73
Human Site: S113 Identified Species: 72.31
UniProt: Q9UJM8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UJM8 NP_060015.1 370 40924 S113 M L S S W A T S S I E E V A E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001116000 370 40848 S113 M L S S W A T S S I E E V A E
Dog Lupus familis XP_542897 370 40870 S113 M L S S W S T S S I E E V A E
Cat Felis silvestris
Mouse Mus musculus Q9WU19 370 40983 S113 M L S S W A T S S I E E V A E
Rat Rattus norvegicus Q07523 353 39183 Y111 V I S S Y A S Y S L E D I V A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514644 368 40523 S113 M L S S W A T S S I E E V A Q
Chicken Gallus gallus XP_415025 373 40953 S113 M L S S W A T S S I E E V A E
Frog Xenopus laevis NP_001086109 356 39447 C111 V A S T Y A T C S V E E I S Q
Zebra Danio Brachydanio rerio NP_001077011 369 40499 S113 M L S S W S T S S I E E V C E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625149 367 40542 S113 I L S T I S T S S I E E V A E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799303 327 35835 R112 I L S S W S T R S I E E V A E
Poplar Tree Populus trichocarpa XP_002330746 369 40517 S111 T L S S W A T S S V E E V A S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LRR9 367 40323 S111 T L S S W A T S S V E E V A S
Baker's Yeast Sacchar. cerevisiae P00175 591 65521 L310 V P Q M I S T L A S C S P E E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.9 90.8 N.A. 89.4 45.4 N.A. 77.8 73.1 51 67.8 N.A. N.A. 50.5 N.A. 54.5
Protein Similarity: 100 N.A. 99.7 96.4 N.A. 97 64.8 N.A. 91.8 88.4 72.9 83.7 N.A. N.A. 72.1 N.A. 68.9
P-Site Identity: 100 N.A. 100 93.3 N.A. 100 33.3 N.A. 93.3 100 40 86.6 N.A. N.A. 73.3 N.A. 80
P-Site Similarity: 100 N.A. 100 100 N.A. 100 80 N.A. 100 100 86.6 93.3 N.A. N.A. 93.3 N.A. 93.3
Percent
Protein Identity: 55.1 N.A. N.A. 54 26.2 N.A.
Protein Similarity: 74.3 N.A. N.A. 74 39.5 N.A.
P-Site Identity: 80 N.A. N.A. 80 13.3 N.A.
P-Site Similarity: 86.6 N.A. N.A. 86.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 65 0 0 8 0 0 0 0 72 8 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 8 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 93 86 0 8 65 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 8 0 0 15 0 0 0 0 65 0 0 15 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 79 0 0 0 0 0 8 0 8 0 0 0 0 0 % L
% Met: 50 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 15 % Q
% Arg: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % R
% Ser: 0 0 93 79 0 36 8 72 93 8 0 8 0 8 15 % S
% Thr: 15 0 0 15 0 0 93 0 0 0 0 0 0 0 0 % T
% Val: 22 0 0 0 0 0 0 0 0 22 0 0 79 8 0 % V
% Trp: 0 0 0 0 72 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 15 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _