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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAO1
All Species:
19.39
Human Site:
S17
Identified Species:
32.82
UniProt:
Q9UJM8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJM8
NP_060015.1
370
40924
S17
D
Y
E
Q
H
A
K
S
V
L
P
K
S
I
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116000
370
40848
S17
D
Y
E
Q
H
A
K
S
V
L
P
K
S
I
Y
Dog
Lupus familis
XP_542897
370
40870
S17
D
Y
E
Q
N
A
K
S
V
L
Q
K
S
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU19
370
40983
S17
D
Y
E
Q
H
V
R
S
V
L
Q
K
S
V
Y
Rat
Rattus norvegicus
Q07523
353
39183
K15
D
F
K
A
H
A
Q
K
Q
L
S
K
T
S
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514644
368
40523
M17
D
Y
E
K
H
A
K
M
V
L
Q
K
S
V
Y
Chicken
Gallus gallus
XP_415025
373
40953
T17
D
F
E
H
Y
A
K
T
F
L
P
K
S
V
Y
Frog
Xenopus laevis
NP_001086109
356
39447
E15
D
F
E
A
Y
A
K
E
N
L
P
K
A
T
W
Zebra Danio
Brachydanio rerio
NP_001077011
369
40499
Q17
D
Y
E
L
R
A
R
Q
I
L
P
K
S
V
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625149
367
40542
Q17
D
F
Q
K
Y
A
D
Q
N
L
T
P
S
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799303
327
35835
T16
D
F
E
D
F
A
T
T
Y
L
P
K
N
A
L
Poplar Tree
Populus trichocarpa
XP_002330746
369
40517
Q15
E
Y
E
A
I
A
K
Q
K
L
P
K
M
V
Y
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LRR9
367
40323
Q15
E
Y
D
A
I
A
K
Q
K
L
P
K
M
V
Y
Baker's Yeast
Sacchar. cerevisiae
P00175
591
65521
Q214
D
F
E
Y
L
A
S
Q
T
L
T
K
Q
A
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
90.8
N.A.
89.4
45.4
N.A.
77.8
73.1
51
67.8
N.A.
N.A.
50.5
N.A.
54.5
Protein Similarity:
100
N.A.
99.7
96.4
N.A.
97
64.8
N.A.
91.8
88.4
72.9
83.7
N.A.
N.A.
72.1
N.A.
68.9
P-Site Identity:
100
N.A.
100
86.6
N.A.
73.3
33.3
N.A.
73.3
60
46.6
53.3
N.A.
N.A.
26.6
N.A.
40
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
66.6
N.A.
86.6
86.6
73.3
80
N.A.
N.A.
60
N.A.
60
Percent
Protein Identity:
55.1
N.A.
N.A.
54
26.2
N.A.
Protein Similarity:
74.3
N.A.
N.A.
74
39.5
N.A.
P-Site Identity:
53.3
N.A.
N.A.
46.6
33.3
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
29
0
93
0
0
0
0
0
0
8
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
86
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
15
0
79
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
43
0
0
8
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
8
36
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
0
0
8
0
0
0
0
22
0
% I
% Lys:
0
0
8
15
0
0
58
8
15
0
0
93
0
0
0
% K
% Leu:
0
0
0
8
8
0
0
0
0
100
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
15
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
15
0
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
58
8
0
0
0
% P
% Gln:
0
0
8
29
0
0
8
36
8
0
22
0
8
0
0
% Q
% Arg:
0
0
0
0
8
0
15
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
8
29
0
0
8
0
58
8
0
% S
% Thr:
0
0
0
0
0
0
8
15
8
0
15
0
8
8
0
% T
% Val:
0
0
0
0
0
8
0
0
36
0
0
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
22
% W
% Tyr:
0
58
0
8
22
0
0
0
8
0
0
0
0
0
58
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _