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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAO1
All Species:
25.15
Human Site:
S230
Identified Species:
42.56
UniProt:
Q9UJM8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.54
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJM8
NP_060015.1
370
40924
S230
K
W
L
R
R
L
T
S
L
P
I
V
A
K
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116000
370
40848
S230
K
W
L
R
R
L
T
S
L
P
I
V
A
K
G
Dog
Lupus familis
XP_542897
370
40870
S230
K
W
L
R
G
L
T
S
L
P
I
V
A
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU19
370
40983
S230
T
W
L
R
R
L
T
S
L
P
I
V
V
K
G
Rat
Rattus norvegicus
Q07523
353
39183
R218
S
L
L
Q
S
I
T
R
L
P
I
I
L
K
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514644
368
40523
S230
K
W
L
K
G
L
T
S
L
P
I
V
A
K
G
Chicken
Gallus gallus
XP_415025
373
40953
S229
K
W
L
R
G
L
T
S
L
P
I
V
A
K
G
Frog
Xenopus laevis
NP_001086109
356
39447
K221
C
W
L
R
S
V
T
K
L
P
I
V
I
K
G
Zebra Danio
Brachydanio rerio
NP_001077011
369
40499
K230
G
W
L
K
T
L
T
K
L
P
V
V
V
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625149
367
40542
K228
K
W
L
K
S
I
T
K
L
P
I
I
L
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799303
327
35835
S227
E
W
L
K
T
I
T
S
L
P
I
I
L
K
G
Poplar Tree
Populus trichocarpa
XP_002330746
369
40517
K224
E
W
L
Q
T
I
T
K
L
P
I
L
V
K
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LRR9
367
40323
K224
Q
W
L
Q
T
I
T
K
L
P
I
L
V
K
G
Baker's Yeast
Sacchar. cerevisiae
P00175
591
65521
K423
E
E
L
K
K
K
T
K
L
P
I
V
I
K
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
90.8
N.A.
89.4
45.4
N.A.
77.8
73.1
51
67.8
N.A.
N.A.
50.5
N.A.
54.5
Protein Similarity:
100
N.A.
99.7
96.4
N.A.
97
64.8
N.A.
91.8
88.4
72.9
83.7
N.A.
N.A.
72.1
N.A.
68.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
46.6
N.A.
86.6
93.3
66.6
60
N.A.
N.A.
60
N.A.
60
P-Site Similarity:
100
N.A.
100
93.3
N.A.
86.6
66.6
N.A.
93.3
93.3
73.3
73.3
N.A.
N.A.
80
N.A.
86.6
Percent
Protein Identity:
55.1
N.A.
N.A.
54
26.2
N.A.
Protein Similarity:
74.3
N.A.
N.A.
74
39.5
N.A.
P-Site Identity:
53.3
N.A.
N.A.
53.3
53.3
N.A.
P-Site Similarity:
80
N.A.
N.A.
80
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
36
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
22
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
22
0
0
0
0
0
0
0
0
0
100
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
36
0
0
0
0
93
22
15
0
0
% I
% Lys:
43
0
0
36
8
8
0
43
0
0
0
0
0
100
0
% K
% Leu:
0
8
100
0
0
50
0
0
100
0
0
15
22
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% P
% Gln:
8
0
0
22
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
43
22
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
8
0
0
0
22
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
29
0
100
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
8
65
29
0
0
% V
% Trp:
0
86
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _