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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAO1
All Species:
20.91
Human Site:
T188
Identified Species:
35.38
UniProt:
Q9UJM8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJM8
NP_060015.1
370
40924
T188
L
R
M
K
N
F
E
T
S
T
L
S
F
S
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116000
370
40848
T188
L
R
M
K
N
F
E
T
S
T
L
S
F
S
P
Dog
Lupus familis
XP_542897
370
40870
T188
L
R
M
K
N
F
E
T
N
D
L
A
F
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU19
370
40983
T188
L
R
M
K
N
F
E
T
N
D
L
A
F
S
P
Rat
Rattus norvegicus
Q07523
353
39183
E176
K
R
N
Q
L
N
L
E
A
N
I
L
L
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514644
368
40523
T188
L
R
M
K
N
F
E
T
S
D
L
A
F
S
S
Chicken
Gallus gallus
XP_415025
373
40953
S187
H
L
R
L
K
N
F
S
S
N
N
L
D
F
S
Frog
Xenopus laevis
NP_001086109
356
39447
L179
N
F
R
L
P
P
H
L
K
V
K
N
F
E
G
Zebra Danio
Brachydanio rerio
NP_001077011
369
40499
S188
L
R
M
A
N
F
E
S
P
D
L
A
F
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625149
367
40542
F186
H
H
L
R
L
G
N
F
Q
G
K
L
S
T
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799303
327
35835
F185
E
P
Y
R
L
A
N
F
T
I
K
T
N
R
G
Poplar Tree
Populus trichocarpa
XP_002330746
369
40517
N182
P
P
F
L
T
L
K
N
F
E
G
L
D
L
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LRR9
367
40323
N182
P
P
N
L
T
L
K
N
F
E
G
L
D
L
G
Baker's Yeast
Sacchar. cerevisiae
P00175
591
65521
K381
K
L
K
F
S
N
T
K
A
G
P
K
A
M
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
90.8
N.A.
89.4
45.4
N.A.
77.8
73.1
51
67.8
N.A.
N.A.
50.5
N.A.
54.5
Protein Similarity:
100
N.A.
99.7
96.4
N.A.
97
64.8
N.A.
91.8
88.4
72.9
83.7
N.A.
N.A.
72.1
N.A.
68.9
P-Site Identity:
100
N.A.
100
80
N.A.
80
6.6
N.A.
80
6.6
6.6
60
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
26.6
N.A.
86.6
13.3
13.3
73.3
N.A.
N.A.
20
N.A.
20
Percent
Protein Identity:
55.1
N.A.
N.A.
54
26.2
N.A.
Protein Similarity:
74.3
N.A.
N.A.
74
39.5
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
6.6
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
15
0
0
29
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
29
0
0
22
0
8
% D
% Glu:
8
0
0
0
0
0
43
8
0
15
0
0
0
8
0
% E
% Phe:
0
8
8
8
0
43
8
15
15
0
0
0
50
8
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
15
15
0
0
0
29
% G
% His:
15
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% I
% Lys:
15
0
8
36
8
0
15
8
8
0
22
8
0
8
22
% K
% Leu:
43
15
8
29
22
15
8
8
0
0
43
36
8
15
0
% L
% Met:
0
0
43
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
15
0
43
22
15
15
15
15
8
8
8
0
0
% N
% Pro:
15
22
0
0
8
8
0
0
8
0
8
0
0
0
29
% P
% Gln:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
50
15
15
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
0
8
0
0
15
29
0
0
15
8
43
15
% S
% Thr:
0
0
0
0
15
0
8
36
8
15
0
8
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _