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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HAO1
All Species:
27.88
Human Site:
Y24
Identified Species:
47.18
UniProt:
Q9UJM8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UJM8
NP_060015.1
370
40924
Y24
S
V
L
P
K
S
I
Y
D
Y
Y
R
S
G
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116000
370
40848
Y24
S
V
L
P
K
S
I
Y
D
Y
Y
R
S
G
A
Dog
Lupus familis
XP_542897
370
40870
Y24
S
V
L
Q
K
S
I
Y
D
Y
Y
R
S
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9WU19
370
40983
Y24
S
V
L
Q
K
S
V
Y
D
Y
Y
R
S
G
A
Rat
Rattus norvegicus
Q07523
353
39183
W22
K
Q
L
S
K
T
S
W
D
F
I
E
G
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514644
368
40523
Y24
M
V
L
Q
K
S
V
Y
D
Y
Y
R
S
G
A
Chicken
Gallus gallus
XP_415025
373
40953
Y24
T
F
L
P
K
S
V
Y
D
Y
Y
R
S
G
A
Frog
Xenopus laevis
NP_001086109
356
39447
W22
E
N
L
P
K
A
T
W
E
Y
Y
A
A
G
A
Zebra Danio
Brachydanio rerio
NP_001077011
369
40499
F24
Q
I
L
P
K
S
V
F
D
Y
Y
F
S
G
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625149
367
40542
R24
Q
N
L
T
P
S
V
R
D
Y
Y
N
S
G
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799303
327
35835
L23
T
Y
L
P
K
N
A
L
D
Y
Y
R
S
G
A
Poplar Tree
Populus trichocarpa
XP_002330746
369
40517
Y22
Q
K
L
P
K
M
V
Y
D
Y
Y
A
S
G
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LRR9
367
40323
Y22
Q
K
L
P
K
M
V
Y
D
Y
Y
A
S
G
A
Baker's Yeast
Sacchar. cerevisiae
P00175
591
65521
W221
Q
T
L
T
K
Q
A
W
A
Y
Y
S
S
G
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
90.8
N.A.
89.4
45.4
N.A.
77.8
73.1
51
67.8
N.A.
N.A.
50.5
N.A.
54.5
Protein Similarity:
100
N.A.
99.7
96.4
N.A.
97
64.8
N.A.
91.8
88.4
72.9
83.7
N.A.
N.A.
72.1
N.A.
68.9
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
26.6
N.A.
80
80
46.6
66.6
N.A.
N.A.
53.3
N.A.
66.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
46.6
N.A.
86.6
93.3
73.3
86.6
N.A.
N.A.
60
N.A.
80
Percent
Protein Identity:
55.1
N.A.
N.A.
54
26.2
N.A.
Protein Similarity:
74.3
N.A.
N.A.
74
39.5
N.A.
P-Site Identity:
66.6
N.A.
N.A.
66.6
46.6
N.A.
P-Site Similarity:
73.3
N.A.
N.A.
73.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
15
0
8
0
0
22
8
0
100
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
86
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
8
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
8
93
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
22
0
0
0
8
0
0
0
0
% I
% Lys:
8
15
0
0
93
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
8
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
58
8
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
36
8
0
22
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
50
0
0
0
% R
% Ser:
29
0
0
8
0
58
8
0
0
0
0
8
86
0
0
% S
% Thr:
15
8
0
15
0
8
8
0
0
0
0
0
0
0
0
% T
% Val:
0
36
0
0
0
0
50
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
22
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
58
0
93
93
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _